ISSN:
1432-069X
Keywords:
Psoriasis
;
T-cell activation
;
CD8 antigen
;
Psoriatic arthritis
;
Atopic dermatitis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Increased levels of the soluble CD8 antigen probably represent a sign of suppressor T-cell activity. The concentration of CD8 was measured in the sera of patients with psoriasis without psoriatic arthritis (n=25) and atopic dermatitis (n=26), exhibiting moderate to severe disease activity, in comparison with nonatopic healthy controls (n=31) using an ELISA technique. CD8 levels were found to be significantly elevated in psoriatic patients as compared with healthy controls (p≤0.002). Increase in CD8 may be due to suppressor T-cell activation in the skin of patients with psoriasis.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00505637
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