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  • 1990-1994  (2)
  • Late Holocene  (1)
  • N-butyl-N-(4-hydroxybuty)nitrosamine  (1)
  • Papillary carcinoma  (1)
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Years
  • 1990-1994  (2)
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  • 1
    ISSN: 1434-0879
    Keywords: N-butyl-N-(4-hydroxybuty)nitrosamine ; N-Methyl-N-nitrosourea ; Rat bladder carcinogenesis ; Papillary carcinoma ; Non-papillary carcinoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The present investigation was conducted to examine the combination effect of N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN) and N-methyl-N-nitrosourea(MNU) in rat urinary bladder carcinogenesis. Experiment 1 was performed in the groups treated by oral BBN administration in combination with MNU intraversical instillation and their control groups. In the groups given both BBN and MNU, the ratio of rats with the nonpapillary type to carcinoma-bearing rats was significantly higher than in the controls. Since most of the carcinomas were non-invasive, the observation period was prolonged in the groups given both BBN and MNU in experiment 2. However, even after a longer observation period, no invasive carcinoma was observed. These results suggest that high-grade and invasive carcinomas similar to those induced by BBN and MNU in the heterotopically transplanted rat bladder cannot be induced in the natural bladder of the rat.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Plant ecology 106 (1993), S. 137-146 
    ISSN: 1573-5052
    Keywords: Late Holocene ; Mangrove habitat development ; Philippines ; Pohnpei Island ; Sea-level change ; Zonation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Using the sites of Pagbilao, the Philippines and Pohnpei Island, the Federated States of Micronesia, zonation and development process of mangrove habitats on tidal flats situated in the geomorphic environment excluding estuary, delta, and lagoon or backmarsh behind barrier or beach ridge were discussed from the viewpoint of geomorphology. Zonations of the mangrove forests were observed from seaward to landward in both areas. Most of the zones correspond with the variations of the ground level or deposit. Mangrove peat which has a thickness of about 2 meters was deposited in the main part of the mangrove habitats in both areas. On the other hand, some large Sonneratia alba were observed in the Rhizophora apiculata habitat on Pohnpei Island. The authors presumed that some of the large S. alba have survived by regeneration from fallen stems since the mangrove forest developed on the present site. The maximum depth of the mangrove peat layer reaches 1.7 meter below the present sea level in Pagbilao and over 2.5 meters at Pohnpei Island. The bottom of the mangrove peat was dated at about 2,000 y.B.P. in both areas by the radiocarbon method. The mangrove peat depositional areas have not been moved during the last 2,000 years. Therefore, the mangrove forests seem to have grown in the present sites since 2,000 y.B.P. and accumulated peat in connection with the subsequent sea-level rise. xx]Nomenclature: Scientific names for mangroves follow Tomlinson (1986). xx]Papers presented at the Vth INTECOL Congress at Yokohama 1990.
    Type of Medium: Electronic Resource
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