ISSN:
1432-1076
Keywords:
Omenn syndrome
;
Hypereosinophilia
;
Endomyocardial disease
;
Bone marrow transplantation
;
Pulmonary vascular obstruction
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract A 5-month-old infant presented with severe combined immunodeficiency disease, reticuloendotheliosis, and hypereosinophilia (Omenn syndrome) resulting in recurrent infections and endomyocardial disease. Bone marrow transplantation from an HLA-identical donor after chemotherapeutic conditioning led to both immunological and clinical recovery. Bone marrow transplantation, however, was followed by severe pulmonary occlusive disease. The patient gradually recovered while on increased inspiratory oxygen and the calcium channel blocker nifedipine.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01955521
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