ISSN:
1432-0533
Keywords:
Pituitary adenoma
;
Neuronal and lipomatous hamartoma
;
Immunocytochemistry
;
Electron micrscopy
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The histological, ultrastructural and immunocytochemical features are reported of an intrasellar neuronal and lipomatous hamartoma associated with pituitary growth hormone (GH) cell adenoma and acromegaly. Electron microscopy demonstrated a close contact between neurons and adenomatous GH cells. By immunohistochemistry the adenoma cells revealed a positive staining for GH and prolactin. the neurons of hamartoma showed neurosecretory activity which might have induced the development of pituitary GH cell adenoma.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00294652
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