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  • 11
    Electronic Resource
    Electronic Resource
    Duodenal atresia (1992)
    Springer
    Pediatric surgery international 7 (1992), S. 435-437 
    Details
    ISSN: 1437-9813
    Keywords: Duodenal atresia ; Duodenal obstruction ; Duodenal stenosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The aim of this study was the assessment of mortality, morbidity, and associated anomalies in a series of 44 patients with congenital intrinsic duodenal obstruction admitted to the Amsterdam Pediatric Surgical Center between 1975 and 1989. Twenty-two patients were girls and 22 were boys. Severe associated anomalies were considered a contraindication for surgery in 8 children. Of the 36 who were operated upon, 8 died within the first year and a half of life. Associated anomalies consisted of trisomy 21 in 11 patients, cardiac defects in 14 (8 with trisomy 21), skeletal defects in 4, esophageal atresia in 3 (in 2 combined with imperforate anus), and various other anomalies in 5. Among the 6 patients with trisomy 21 who were operated upon, 3 died within 18 months after surgery. The surviving 3 in this group are all below the normal average weight for age. All patients without associated anomalies did well postoperatively. One patient developed a bowel obstruction at age 2 years. It appears from this study that the eventual outcome in children with duodenal atresia is determined almost exclusively by the presence or absence of associated anomalies.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00178823
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  • 12
    Electronic Resource
    Electronic Resource
    Primary segmental infarction of the greater omentum in children (1990)
    Springer
    Pediatric surgery international 5 (1990), S. 224-227 
    Details
    ISSN: 1437-9813
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00179672
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  • 13
    Electronic Resource
    Electronic Resource
    1:2 complexes of (thio)morpholinium derivatives and the electron acceptor 7,7,8,8-tetracyano-p-quinodimethane. VII. Triclinic form of N,N-dimethylmorpholinium di-7,7,8,8-tetracyano-p-quinodimethanide, DMM(TCNQ)2 (II), at 294 K (1994)
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 50 (1994), S. 1139-1141 
    Details
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108270193011199
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  • 14
    Electronic Resource
    Electronic Resource
    Differential depolarization-activated calcium responses in fetal and neonatal rat osteoblast-like cells (1994)
    Springer
    Calcified tissue international 54 (1994), S. 278-283 
    Details
    ISSN: 1432-0827
    Keywords: Calcium channels ; Development ; Osteoblastic cells ; Fura-2 ; Patch-clamp
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract The present study evaluates differential occurrence of voltage-dependent calcium channels (VDCC) in the membranes of fetal (FROB) and neonatal (NROB) calvarian rat osteoblastic cells in primary culture. The intracellular calcium concentration ([Ca2+]i) was monitored upon depolarization of the cell membrane with the use of high K+ containing extracellular solutions. [Ca2+]i was measured in populations of cells as well as in individual cells using Fura-2, whereas the membrane potential (Em) was recorded in parallel experiments using patch-clamp techniques. Increasing the extracellular K+ concentration resulted in an instantaneous depolarization of Em of both FROB and NROB. This depolarization of Em did not significantly affect [Ca2+]i of populations of FROB and neonatal osteoblast precursors (NpROB). In contrast to FROB and NpROB, NROB populations responded to depolarization with significant transient [Ca2+]i increases that could be blocked by the calcium antagonist verapamil and were absent if extracellular Na+ was replaced for choline instead of K+. In individual cell measurements, response frequencies as well as the magnitude of [Ca2+]i responses upon depolarization of NROB were much higher than those of FROB, suggesting that more NROB than FROB possess VDCC. This phenomenon might point to a development-related expression of VDCC in the membranes of osteoblast-like cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00295951
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  • 15
    Electronic Resource
    Electronic Resource
    Incidence of forearm and hand ischaemia related to radial artery cannulation in newborn infants (1990)
    Springer
    Intensive care medicine 16 (1990), S. 50-53 
    Details
    ISSN: 1432-1238
    Keywords: Radial artery catheter ; Ischaemia ; Newborn infants
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report the incidence of transient and permanent ischaemia of the forearm and hand caused by radial artery cannulation in a series of 98 newborn infants. Birth weight ranged from 550 to 3920 g (median 1600 g) and gestational age ranged from 26 to 40 weeks (median 31 weeks). In 4 of the 98 infants transient ischaemia of the forearm and/or hand occurred. In three infants the onset of ischaemia was probably related to thrombo-embolic events and in one infant to inadequate palmar collateral circulation. Permanent ischaemic damage with tissue loss did not occur in any infant. It is concluded that permanent ischaemic damage to the forearm and/or the hand with tissue loss, attributable to radial artery cannulation, is seldom encountered in newborn infants. In minimizing the risk of ischaemia, careful assessment of palmar collateral circulation prior to cannulation and of all factors predisposing to the onset of ischaemia is essential. Immediate removal of the catheter at the earliest signs of ischaemia, is essential to prevent ensuing tissue loss.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01706325
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  • 16
    Electronic Resource
    Electronic Resource
    Hypertension associated with skeletal traction in children (1993)
    Springer
    Pediatric nephrology 7 (1993), S. 386-386 
    Details
    ISSN: 1432-198X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00857545
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  • 17
    Electronic Resource
    Electronic Resource
    Risks and benefits of antireflux operations in neurologically impaired children (1994)
    Springer
    European journal of pediatrics 153 (1994), S. 248-251 
    Details
    ISSN: 1432-1076
    Keywords: Gastro-oesophageal reflux ; Neurologically impaired children ; Anterior gastropexy Gastrostomy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Gastro-oesophageal reflux (GER) in neurologically impaired children often causes feeding problems and complications of oesophagitis and is frequently resistant to medical treatment. Fifty neurologically impaired children underwent anterior gastropexy as anti-reflux operation, combined with gastrostomy in 23, between 1976 and 1992. There was no operative mortality. There were 25 early complications in 14 patients and 9 late complications in 9 patients. Twelve patients needed 17 re-operations for delayed gastric emptying [4], intestinal obstruction [3], para-oesophageal hernia [3], oesophageal stenosis [4], and recurrent GER, revision of gastrostomy, subphrenic abcess (one each). Nine patients died during the follow up period. Death in two children was related to the operation (incarcerated para-oesophageal hernia and blowout of the stomach). Out of 41 survivors, the operation was judged successful in 35. It is concluded that antireflux operations in neurologically impaired children carry a high risk of complications. Preoperative identification of risk factors is not possible. The improvements in the quality of life achieved in the majority of patients outweigh the risks.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01954512
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  • 18
    Electronic Resource
    Electronic Resource
    Incidence and duration of total occlusion of the radial artery in newborn infants after catheter removal (1990)
    Springer
    European journal of pediatrics 149 (1990), S. 275-277 
    Details
    ISSN: 1432-1076
    Keywords: Percutaneous radial artery cannulation ; Newborn infants ; Radial artery occlusion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The incidence and duration of total occlusion of the radial artery after catheter removal was determined using repeated Doppler flow measurements. Thirty-two newborn infants with birthweights ranging from 945 g to 3890 g (median 1935 g) and gestational age ranging from 26 to 40 weeks (median 32 weeks) were studied. In 20 out of 32 infants (63%), complete occlusion of the radial artery occurred. The number of occlusions were not related to birthweight, gestational age or duration of cannulation. In all infants, blood flow in the radial artery resumed within 1–29 days after catheter removal. The duration of occlusion was directly related to the duration of cannulation and inversely related to birthweight. This study demonstrates a high frequency of total occlusion of the radial artery in newborn infants after percutaneous radial artery cannulation. In the majority of infants with a radial artert catheter, blood flow to the tissue distal to the cannulation site is dependent solely on the existence of an adequate arterial palmar collateral circulation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02106293
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  • 19
    Electronic Resource
    Electronic Resource
    Risks and benefits of antireflux operations in neurologically impaired children (1994)
    Springer
    European journal of pediatrics 153 (1994), S. 248-251 
    Details
    ISSN: 1432-1076
    Keywords: Key words: Gastro-oesophageal reflux – Neurologically impaired children – Anterior gastropexy – Gastrostomy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Gastro-oesophageal reflux (GER) in neurologically impaired children often causes feeding problems and complications of oesophagitis and is frequently resistant to medical treatment. Fifty neurologically impaired children underwent anterior gastropexy as anti-reflux operation, combined with gastrostomy in 23, between 1976 and 1992. There was no operative mortality. There were 25 early complications in 14 patients and 9 late complications in 9 patients. Twelve patients needed 17 re-operations for delayed gastric emptying [4], intestinal obstruction [3], para-oesophageal hernia [3], oesophageal stenosis [4], and recurrent GER, revision of gastrostomy, subphrenic abcess (one each). Nine patients died during the follow-up period. Death in two children was related to the operation (incarcerated para-oesophageal hernia and blow-out of the stomach). Out of 41 survivors, the operation was judged successful in 35. It is concluded that antireflux operations in neurologically impaired children carry a high risk of complications. Preoperative identification of risk factors is not possible. The improvements in the quality of life achieved in the majority of patients outweigh the risks.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01954512
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    Paper (German National Licenses)
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  • 20
    Electronic Resource
    Electronic Resource
    Hypertension associated with skeletal traction in children (1992)
    Springer
    European journal of pediatrics 151 (1992), S. 543-545 
    Details
    ISSN: 1432-1076
    Keywords: Arterial hypertension ; Skeletal traction ; Fractures ; Children ; Hypercalcaemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Since traction-associated hypertension seems to be a relatively unknown phenomenon, a survey was done of its incidence in children treated with skeletal traction for fractures and orthopaedic diseases. The correlation with hypercalcaemia, a possible aetiological factor, was also explored. Blood pressure was recorded three times a day with an automatic oscillometric unit during the stay in the hospital. Serum calcium, creatinine and total protein concentrations were measured once a week. Patients with pre-existing diseases or renal trauma were excluded. Arterial hypertension (systolic and/or diastolic) was found in 31/50 children (62%). In almost half of these the rise in systolic blood pressure was 10 mmHg or more above the 95th percentile. Hypertension occurred in most cases within the first 3 weeks of treatment; in 7 children it developed after 3 or more weeks of traction. All children became normotensive within 1 week after discontinuation of traction. Clinical symptoms were rare: two children complained of headache. In no instance had traction to be discontinued before the planned date because of hypertension. In the hypertensive group were more preschool children and more humeral fractures as compared to the normotensive group (n=19). Hypercalcaemia occurred in 11 children and was equally distributed in hypertensive and in normotensive children. It is concluded that arterial hypertension is a frequent finding in children in traction, but its clinical relevance is uncertain. Hypercalcaemia is not a rare finding in immobilized children, but probably plays no causative role in traction-related hypertension.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01957765
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