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  • 1990-1994  (3)
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  • 1
    ISSN: 1439-0973
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Wir berichten über eine hämatogen entstandene Endophthalmitis durchSerratia marcescens bei einem HIV-infizierten I.-v.-Drogenabhängigen. Bei Aufnahme bestanden Fieber, Augenschmerzen und Sehverlust des rechten Auges. Die Beschwerden waren nach intravenöser Injektion von Bupremorphin-Pulver aufgetreten. Aus Kammerwasser wurdeS. marcescens angezüchtet. Der Patient wurde i.v. mit Ceftriaxon (2 g zweimal täglich) und Amikacin (500 mg zweimal täglich) und oral mit Fosfomycin (1 g viermal täglich) drei Wochen lang behandelt. Die Augeninfektion wurde geheilt, doch kam es zu einem zur Erblindung führenden Sehverlust. Unseres Wissens ist dies der zweite Fall einerS. marcescens-Endophthalmitis bei einem I.-v.-Drogenabhängigen, der in der englischsprachigen Literatur mitgeteilt wird.
    Notes: Summary A case of haematogenousSerratia marcescens endophthalmitis in an HIV-infected intravenous drug addict is described. The patient was admitted with fever, ocular pain and visual loss in the right eye following an i.v. injection of pulverized bupremorphine. A vitreous humor culture grewS. marcescens. The patient was treated with i.v. ceftriaxone (2 g b. i. d.), i.v. amikacin (500 mg b. i. d.) and p. o. fosfomycin (1 g q. i. d.) for three weeks. The ocular infection was cured, although the visual function was lost, leading to blindness. To our knowledge, this is the second case in the reviewed Anglo Saxon literature ofS. marcescens endophthalmitis in parenteral drug addicts.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1439-0973
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei einer 79 Jahre alten Frau trat acht Jahre nach Aortenklappenersatz mit einer Bioprothese aus Perikard vom Rind eine Klappenprothesen-Endokarditis auf, als deren UrsacheCorynebacterium pilosum identifiziert wurde. Trotz Antibiotikatherapie kam es zu einem letalen Verlauf der Erkrankung.
    Notes: Summary A case of prosthetic valve endocarditis caused byCorynebacterium pilosum in a 79-year-old woman developed eighty years after aortic valve replacement with bovine pericardium bioprosthesis is described. In spite of the antibiotic therapy she presented an unfavourable course that led to her death.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In a prospective study sixty-eight patients consecutively diagnosed as having AIDS or advanced ARC who were started on zidovudine therapy were followed up for a median period of 725 days. In the 20 patients who had a baseline p24 antigen level above 20 pg/ml, there was a statistically significant trend towards reduction of the p24 antigen levels after the first month of treatment. The median time of survival of the 68 patients was 702 days and the median symptom-free period was 510 days. Treatment with zidovudine significantly reduced the p24 antigen levels. However, the life expectancy and the symptom-free period were not statistically different in the patients with p24 antigen levels always below or with levels always above two arbitrarily chosen cut-off points of 20 pg/ml and 50 pg/ml, respectively.
    Type of Medium: Electronic Resource
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