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  • 1985-1989  (1)
  • 1980-1984  (3)
  • 1975-1979
  • 1940-1944
  • Aplastic anaemia  (2)
  • Aluminium  (1)
  • Bimodal local-density random-walk distribution  (1)
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Material
Years
  • 1985-1989  (1)
  • 1980-1984  (3)
  • 1975-1979
  • 1940-1944
Year
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Anti-thymocyte globulin (ATG) can eliminate platelet refractoriness (1981)
    Springer
    Annals of hematology 42 (1981), S. 331-335 
    Details
    ISSN: 1432-0584
    Keywords: ATG ; Aplastic anaemia ; Platelet transfusion ; Immunosuppression
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Of the 14 patients with aplastic anaemia treated in our hospital with anti-thymocyte globulin (ATG), four were refractory to random platelets before therapy due to the presence of leucocyte antibodies. In contrast to the ten non-refractory patients in whom no success was obtained, three of the four refractory patients showed haematological improvement after ATG. Additionally, two patients could be substituted again with random platelets. The other two hardly needed platelet-transfusions after ATG, and they were given HLA-compatible platelets. To determine the degree of immunosuppression, these four patients were tested for the presence of antibodies against leucocytes and two endemic viruses, i.e., mumps and rubella virus. Before ATG, all sera reacted with almost the whole leucocyte testpanel. After treatment, the leucocyte antibodies disappeared completely in three patients. In one patient there was no dramatic change. In all patients, however, the antibody-titre against the mumps and rubella viruses remained constant and there was only a slight decrease in total IgG content in the three “suppressed” patients. We conclude that it might be worthwile to study systematically the selective immuno-suppressive effect of ATG.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00996895
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Serum inhibitors in aplastic anaemia (1982)
    Springer
    Annals of hematology 44 (1982), S. 193-200 
    Details
    ISSN: 1432-0584
    Keywords: Serum inhibitors ; CFU-c ; Aplastic anaemia ; HLA-antibodies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary To study the frequency and clinical importance of serum factors inhibiting CFU-c in patients with aplastic anaemia, sera from 21 patients were analysed. The sera of eight patients showed inhibition of at least one normal bone marrow, but strong and consistent inhibition of two or more normal bone-marrow samples was found in only two cases. In both of these two patients the inhibition disappeared after successful therapy. Fair, but not complete, correlation was found between serum hibitors and HLA-antibodies, suggesting that at least part of these inhibitors are antibodies directed against HLA-antigens present on myeloid progenitor cells. Serum inhibitors appear to be infrequent in the population of patients with aplastic anaemia seen in our hospital and appear to have no major implications for therapy or outcome of the disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00319904
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    The effect of air-borne ammonium sulphate onPinus nigra var.maritima in the Netherlands (1985)
    Springer
    Plant and soil 84 (1985), S. 45-56 
    Details
    ISSN: 1573-5036
    Keywords: Acidification ; Air pollution ; Aluminium ; Ammonium sulphate ; Nitrification ; Nutrient leaching ; Pinus nigra var.Maritima ; Potassium deficiency
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Summary As a result of air pollution, considerable deposition of ammonium sulphate occurs on vegetation and soil in the vicinity of chicken farms and fields dressed with animal slurry. A clear relation exists between this ammonium sulphate deposition and the distance to certain agricultural activities. Field investigations and ecophysiological experiments both show that the needles ofPinus nigra var.maritima (Ait.) Melville take up ammonium and excrete potassium, magnesium and calcium. This often results in potassium and/or magnesium deficiencies and may lead to premature shedding of needles. The high levels of nitrogen in the needles are strongly correlated to fungal diseases. Whether the observed cation leaching will result in disturbed nutrient budgets depends mainly on soil conditions. Leaching of K, Mg and Ca from the soil, caused by ammonium sulphate, may further inhibit nutrient uptake. Field investigations show a clear correlation between increased ratios of NH4 to K, Mg and Ca in the soil solution and the damage to pine forests.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02197866
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Interpretation of circulatory shunt-dilution curves as bimodal distribution functions (1984)
    Springer
    Medical & biological engineering & computing 22 (1984), S. 326-332 
    Details
    ISSN: 1741-0444
    Keywords: Bimodal local-density random-walk distribution ; Curve fitting, Indicator dilution technique ; Quantitative determination of shunts
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract A technique for automatic computation of circulatory shunts from indicator-difution curves is presented. In the case of shunts, dilution curves over the heart and pulmonary circulation comprise two primary curves occasionally with a marked, mutual overlap Quantitative determination of a right to left or left to-right shunt is based on a mathematical spearation of the shunt-dilution curve into the component primary curves. A mathematical model of the bimodal distribution of indicator transit times has been fitted directly to a complete shunt-dilution curve. This model is based on a local-density random-walk approach. Validation of the model is performed by simulations of shunt-dilution curves both mathematically and with a hydrodynamic circulation model. Analysis of the curves. Shows that the technique presented provides reliable and accurate estimates of the amount of shunt even in cases of marked overlap of the primary curves, in which the techniques usually applied are inaccurate or inadequate. This conclusion is confirmed in animal experiments in which we have estimated right-to-left shunts through the torament ovale of newborn pigs
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02442101
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    Paper (German National Licenses)
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