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  • 1
    Electronic Resource
    Electronic Resource
    Two types of delayed traumatic intracerebral hematoma: Differential forms of treatment (1989)
    Springer
    Neurosurgical review 12 (1989), S. 231-236 
    Details
    ISSN: 1437-2320
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01790655
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  • 2
    Electronic Resource
    Electronic Resource
    Granulocyte adhesion to nephritic glomeruli through recognition of activated C4 and C3 in immune deposits (1985)
    Springer
    Cellular and molecular life sciences 41 (1985), S. 1456-1457 
    Details
    ISSN: 1420-9071
    Keywords: Granulocyte ; complement ; immune adherence ; immune deposit ; glomerulonephritis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Sections of rat kidney with bovine serum albumin nephritis were incubated either with a single component of complement or with several components in sequence and then reacted with granulocytes. The average number of granulocytes bound to a nephritic glomerulus was elevated in sections incubated with C4 or C3 and increases were most significant when C14, C142 or C1423 were incubated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01950033
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  • 3
    Electronic Resource
    Electronic Resource
    Ultrasonic demonstration of a common bile duct calculus associated with congenital bile duct dilatation (1988)
    Springer
    Pediatric radiology 18 (1988), S. 499-500 
    Details
    ISSN: 1432-1998
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A 8-year-old Japanese girl had congenital bile duct dilatation, associated with both choledocholithiasis and acute pancreatitis. Ultrasonography (US) was used to demonstrate a stone within a dilated common bile duct, and US provides the most useful preoperative information to proceed to surgery.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00974091
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  • 4
    Electronic Resource
    Electronic Resource
    Infantile spasms: Etiological factors, clinical aspects, and long term prognosis in 200 cases (1981)
    Springer
    European journal of pediatrics 135 (1981), S. 239-244 
    Details
    ISSN: 1432-1076
    Keywords: Infantile spasms ; Etiological factors ; Clinical aspects ; Long term prognosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The etiological factors, clinical aspects and long term prognosis were studied in 200 patients with infantile spasms. Forty-eight (24.0%) died and the rest were aged 6 years or more at the time of final follow-up. In 73 (36.5%) the etiology was prenatal, in 44 (22.0%) perinatal, and in 17 (8.5%) postnatal: 18 cases (9.0%) were cryptogenic. The remaining 48 (24.0%) patients were doubtful cases. The mortality of the pre-and perinatal cases at 35.6% and 34.1% respectively was significantly higher than that in the other etiologic groups (P〈0.001). With regard to the onset of spasms, these were very carly in the pre-and perinatal groups, whereas in the postnatal group the onset was late. The onset in the doubtful and cryptogenic groups was in between. Some 44.4% of the cryptogenic cases showed normal mental and physical development after the age of 6 years, whereas less than 10% of the prenatal and perinatal group did so. Almost all of the doubtful cases became mentally subnormal. The incidence of a family history of epilepsy or other convulsive disorders in the first, second and third degree relatives was highest in the cryptogenic cases (40.0%), and lowest in the perinatal cases (9.3%) (P〈0.01). The incidence of laughing attacks was highest in the postnatal cases (42.9%), against no such attacks in cryptogenic cases (P〈0.01). The attacks seemed to be linked with organic brain lesions. Among various factors related to the etiology of infantile spasms, genetic propensity seemed especially important in cryptogenic cases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00442097
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  • 5
    Electronic Resource
    Electronic Resource
    The value of EEG and cerebral evoked potentials in the assessment of neonatal intracranial hemorrhage (1981)
    Springer
    European journal of pediatrics 137 (1981), S. 177-184 
    Details
    ISSN: 1432-1076
    Keywords: EEG ; Evoked potentials ; Newborn ; Intracranial hemorrhage
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The EEG, visual and auditory evoked potentials (VEP, AEP) were evaluated in 16 full-term newborn infants who had intracranial hemorrhage documented by computerized tomography (CT). Three of them had supratentorial, three, supra- and infratentorial hemorrhage, while the other ten had infra- or peri-tentorial bleeding. Three died during the neonatal period. Eight of the 13 surviving infants were neurologically normal and five were abnormal at the time of the follow-up. Those who had normal or mildly abnormal background EEGs all developed normally, while those whose neonatal EEG was severely abnormal subsequently developed neurological sequelae irrespective of the extent of intracranial hemorrhage. The EEG, VEP or AEP is of little value in the diagnosis of intracranial bleeding but the EEG is valuable in assessing the degree of associated parenchymatous damage and is of great prognostic significance.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00441313
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  • 6
    Electronic Resource
    Electronic Resource
    High doses of gamma globulin and methylprednisolone therapy for idiopathic thrombocytopenic purpura in children (1985)
    Springer
    European journal of pediatrics 144 (1985), S. 240-242 
    Details
    ISSN: 1432-1076
    Keywords: Idiopathic thrombocytopenic purpura ; Gamma globulin ; Methylprednisolone
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In four children with chronic idiopathic thrombocytopenic purpura (ITP), high doses of gamma globulin or methylprednisolone were effective in increasing platelet counts transiently, yet there was no quantitative relationship between the platelet responses to these two therapies. This finding suggests a qualitative difference in the mechanisms of increasing platelets by the two drugs. High doses of gamma globulin and methylprednisolone showed a synergistic effect on the initial and maximal platelet responses, suggesting an intensification of the effect of gamma globulin by methylprednisolone. This combination therapy should be clinically useful, particularly in the control of acute haemorrhage or in preparations for emergency surgery.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00451950
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  • 7
    Electronic Resource
    Electronic Resource
    Immunological characterization of serine hydroxymethyltransferase of methylotrophic Hyphomicrobium strains (1987)
    Springer
    Archives of microbiology 147 (1987), S. 328-333 
    Details
    ISSN: 1432-072X
    Keywords: Serine hydroxymethyltransferase ; Anti-serine hydroxymethyltransferase serum ; Hyphomicrobium ; Methylotroph ; Cross-reaction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Antisera were prepared against homogeneous serine hydroxymethyltransferase (SHMT) of an obligate methylotroph, Hyphomicrobium methylovorum GM2. Cell-free extracts of methylotrophic and non-methylotrophic microorganisms, rat and rabbit liver, which showed SHMT activities, were tested for immunological corss-reactivity with the anti-H. methylovorum GM2-SHMT. The extracts of only six methylotrophic strains showed reactivities These bacterial strains were all found to belong to the genus Hyphomicrobium on the basis of electron microscopy and C1-compound utilization. The cross-reaction test using the anti-H. methylovorum GM2-SHMT was also applied to various Hyphomicrobium strains. With the exception of H. neptunium, which has previously been recommended to be transferred to another genus, cell-free extracts of all the strains formed precipitin lines; some of them fused and the other spurred with each other. Thus, it was concluded that SHMT enzymes of methylotrophic Hyphomicrobium strains are immunologically related closely to each other and that the SHMT of H. methylovorum is an antigen specific for the genus Hyphomicrobium.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00406128
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  • 8
    Electronic Resource
    Electronic Resource
    Immunological studies on histiocytosis X. I. Special reference to the chemotactic defect and the HLA antigen (1986)
    Springer
    Journal of clinical immunology 6 (1986), S. 355-362 
    Details
    ISSN: 1573-2592
    Keywords: Histiocytosis X ; chemotaxis ; chemiluminescence ; HLA antigens
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We treated a family with three children with histiocytosis X (H-X). The chemotactic response of the neutrophils in these three patients was depressed and the chemotactic response of the neutrophils of the mother was also depressed compared to that of normal age-matched controls. To elucidate the genetic factors, we examined HLA antigens in five members of this family. All five members had Aw24, B7, Cw7, and DR1. Immunological and genetic studies in an additional 32 patients with H-X were performed. The chemotactic response of 35 patients with H-X (154.9±58.4/HPF) was significantly depressed in comparison with that of 35 age-matched healthy controls (613.3±116.7/HPF). In addition, the value of chemiluminescence of 20 of 35 patients (20.5±6.6 mV) was also significantly depressed in comparison with that of 20 normal controls (45.3±11.4 mV). The frequencies of Bw61 (54.4%) and Cw7 (45.4%) in 33 patients with H-X were significantly increased in comparison with those of 250 normal healthy controls (20.4 and 18.0%, respectively). Studies of immunoglobulin levels and complement titers of patients with H-X showed no consistent abnormalities. We proposed that defects of polymorphonuclear function may lead to an increased susceptibility to bacterial infections in patients with this disorder.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00915374
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  • 9
    Electronic Resource
    Electronic Resource
    Traffic-alarm sound monitor for aurally handicapped drivers (1987)
    Springer
    Medical & biological engineering & computing 25 (1987), S. 68-74 
    Details
    ISSN: 1741-0444
    Keywords: Aurally handicapped ; Alarm monitor ; Driving ; Electronic aid
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract There are several countries in the world in which people with severe hearing loss are not eligible for a car driver’s licence. As a technical approach to solve this problem, an electronic device has been developed which detects traffic-alarm sounds, i.e. horns of cars, sirens of emergency vehicles, and alarm signals of railway crossings, and then displays them as a light signal to the driver. The basic operating principle of the device is that those traffic-alarm sounds have sharp line spectra in the frequency domain whereas ambient traffic noise is wide-band random noise. The real time detection of the line spectra, masked by random noise, is realised by use of a phase-locked loop and a simplified lock-in amplifier. The results of simulation experiments and road tests demonstrate that the performance of the device is satisfactory except in the case of the detection of the alarm signal of a railway crossing.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02442823
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  • 10
    Electronic Resource
    Electronic Resource
    Capacitive transducer for continuous measurement of vertical foot force (1984)
    Springer
    Medical & biological engineering & computing 22 (1984), S. 309-316 
    Details
    ISSN: 1741-0444
    Keywords: Capacitive transducer ; Error analysis ; Foot force ; Gait analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract A capacitive transducer is developed which continuously measures the vertical component of foot forces during walking. The transducer is shaped like an insole and consists of two subtransducer units, the front and rear. The outputs of the two units are summed to give the total force exerted by the foot. Each unit has a multilayered structure. The basic layer is a 2 mm Neoprene sponge sheet sandwiched by two 50 μm copper foils. They as a whole form a capacitor. The other two layers are a driving shield and static shield, which minimise the effect of stray capacitance and power-line noise, respectively. The transducer is thin (3·8 mm), light (90 g) and flexible and so does not hinder the natural gait pattern. It can be attached to the sale of the shoe easily by elastic bands and Velcro straps. The accuracy of the transducer is well within ±10 per cent of the full scale. An error analysis is made to clarify the change in sensitivity owing to a localised foad. The results are used to compensate for the inherent nonlinearity of the transducer units.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02442098
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