ISSN:
1573-8221
Keywords:
zona pellucida
;
blastocyst
;
17β-estradiol
;
prostaglandin F2α
;
mitosis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract The effect of prostaglandin F2α (2 mg/kg at each stage of development) on the preimplantation development of mice and on their plasma 17β-estradiol concentration was investigated. Prostaglandin F2α inhibited mitotic division in the embryo and reduced the percentage of embryos shedding the zona pellucida. Meanwhile the 17β-estradiol concentration in the peripheral blood plasma fell. Under physiological conditions there was a significant increase in the 17α-estradiol concentration at the blastocyst stage after shedding of the zona pellucida.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00838205
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