ISSN:
1573-8221
Keywords:
bradykinin
;
action block
;
cyproheptadine
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract The effect of cyproheptadine, an inhibitory of serotonin and histamine, on the effects of exogenous and endogenous bradykinin was investigated. Cyproheptadine inhibited the effect of bradykinin on a segment of guinea pig intestine in vitro, abolished the hypotensive action of bradykinin on rats in vivo, and blocked constriction of the blood vessels of the rabbit ear and the fall in the blood kininogen level caused by injection of pyrogenal.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00809870
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