ISSN:
1432-0738
Keywords:
Bromisovalerianylcarbamide
;
Methaqualone-Meprobamate-Poisoning
;
Gastric/Intestinal Lavage
;
Forced Diuresis
;
Extracorporeal Dialysis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Description / Table of Contents:
Zusammenfassung Eine schwere Bromisovalerianylcarbamid-, Methaqualonund Meprobamatvergiftung (Nyktogen®), die mit tiefer Bewußtlosigkeit, Axeflexie, Atemstörungen, klonisch-tonischen Krampfanfall, tiefgreifenden EEG-Veränderungen und toxischer Leberschädigung einherging, konnte bei einem 12 Jahre alten Knaben durch intensive Behandlung mit fortlaufenden Magen- und Darmspülungen, forcierter Diurese und extracorporaler Dialyse beherrscht werden. Auf Grund der Bromiduntersuchungen im Serum und Mageninhalt zeigte sich, daß forcierte Magenspülungen und Darmspülungen als die wesentlichen Maßnahmen in der Therapie
Notes:
Abstract A 12-year-old boy who had ingested large amounts of bromisovalerianyl-carbamide-methaqualone-meprobamate (Nyctogen®) and was suffering from coma, respiratory distress, convulsions, areflexia, dysrhythmias in the EEG, and toxic liver damage was successfully treated by means of prolonged and repeated gastric and intestinal lavage, forced diuresis and extracorporeal dialysis. On the basis of the bromide analysis in the serum and the gastric lavage fluid, it seems that forced gastric and intestinal lavage are the essential therapeutic measures in case of Bromural poisoning. This conclusion was drawn from observation of the present case. The conditions of absorption and reabsorption of the toxic substances were especially unfavorable, because of a paralytic ileus. The fact that extracorporeal hemodialysis had no effect in our case is partly due to the low blood-concentration of bromide and possibly partly to the low dialysability of Meprobamate.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02425926
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