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  • 1
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Physics of Fluids 28 (1985), S. 1248-1252 
    ISSN: 1089-7666
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The numerical continuation and bifurcation methods of Keller [H. B. Keller, in Applications of Bifurcation Theory (Academic, New York, 1977), pp. 359–384] are used to study the variation of some branches of axisymmetric Taylor vortex flow as the wavelength in the axial direction changes. Closed "loops'' of solutions and secondary bifurcations are determined. Variations with respect to Reynolds number show the same phenomena. The results presented here show that Taylor vortices with periodic boundary conditions exist in a wider range of wavelengths, λ, than observed in the Burkhalter/Koschmieder experiments [Phys. Fluids 17, 1929 (1974)]. They also show that there is possibly a λ subinterval within the neutral curve of Couette flow such that there are no Taylor vortex flows with smallest period in this interval.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Analytical chemistry 35 (1963), S. 400-402 
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
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    Unknown
    Oxford : Periodicals Archive Online (PAO)
    Medium aevum. 36 (1967) 185 
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    World journal of surgery 10 (1986), S. 53-63 
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé La dénutrition représente un facteur de risque important chez les malades qui doivent subir une intervention gastro-intestinale majeure. En 7–10 jours, une alimentation parentérale préopératoire est susceptible d'améliorer l'état nutritif de la majorité des sujets dénutris. La concentration de divers facteurs protéiques et l'immunocompétence augmentent de manière significative. Les conséquences de l'alimentation parentérale préopératoire ont été étudiées avec précision seulement lors de quelques essais comparatifs. Les résultats de ces études n'ont pas toujours été identiques. Cependant, on peut dire que lorsque le taux des complications postopératoires était élevé il s'est trouvé réduit. L'amélioration de la technique chirurgicale limite cependant la valeur de ce fait. En réalité, on peut considérer que l'alimentation parentérale restera indiquée jusqu'à ce que le taux des complications opératoires devienne nul, en particulier lorsque le malade est traité pour un cancer de la partie supérieure du tube digestif par une intervention majeure.
    Abstract: Resumen La malnutrición puede ser un importante factor de riesgo, especialmente en pacientes sometidos a cirugía gastrointestinal mayor. Mediante la provisión de siete a diez días de nutrición parenteral preoperatoria adecuada, hemos sido capaces de mejorar el estado nutricional de la mayoría de los pacientes. Las concentraciones de los diversos parámetros de los compartimientos proteicos y de la inmunocompetencia aparecen significativamente incrementadas. El efecto de la nutrición parenteral preoperatoria sobre el resultado postoperatorio ha sido estudiado sólo en unos pocos ensayos clínicos debidamente diseñados: los resultados no han sido unánimes. Sólo si la tasa de complicaciones postoperatorias ha sido alta, la nutrición parenteral preoperatoria aparece disminuyéndola en forma significativa. Las mejores técnicas quirúrgicas han venido a limitar el valor de la nutrición parenteral preoperatoria. Pero mientras la tasa de complicaciones postoperatorias no llegue a 0, la nutrición parenteral preoperatoria tendrá significación, especialmente en pacientes con cáncer del tracto gastrointestinal alto, para quienes se planea una operación mayor.
    Notes: Abstract Malnutrition can be an important risk factor, especially in patients undergoing major gastrointestinal surgery. With 7–10 days of adequate preoperative parenteral nutrition, we are able to improve the nutritional status of most patients. Concentrations of several parameters of the protein compartment and immunocompetence increase significantly. The effect of preoperative parenteral nutrition on postoperative outcome has been tested in only a few properly designed comparative trials. The results were not unanimous. If the postoperative complication rate was high, preoperative parenteral nutrition significantly reduced it. Improvement in surgical technique limited the value of preoperative parenteral nutrition. However, as long as the postoperative complication rate is not zero, preoperative parenteral nutrition is indicated, especially in patients with cancer of the upper gastrointestinal tract, when a major operation is planned.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 334 (1986), S. 346-351 
    ISSN: 1432-1912
    Keywords: Nerve growth factor (NGF) ; Rat basal forebrain ; Cholinergic neurons ; Monoaminergic neurons ; Denervation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We have investigated whether degeneration of basal forebrain cholinergic neurons is a potential trigger for increased NGF production in the adult rat brain. Electrolytic lesions of cholinergic neurons in the septum-diagonal band and in the nucleus basalis of Meynert induced a transient increase in NGF in the ventral hippocampus (+70%) and cerebral cortex (+125%), respectively. In contrast, selective aminergic denervation of the forebrain by electrolytic lesion of the medial forebrain bundle, did not increase NGF levels in hippocampus and cerebral cortex. Thus, a cholinergic mechanism appears to regulate NGF production in adult rat basal forebrain.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 335 (1987), S. 12-20 
    ISSN: 1432-1912
    Keywords: MAO-A ; MAO-13 ; Short-acting MAO inhibitors ; In vitro reversibility ; Rat brain and liver
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The inhibition of monoamine oxidase (MAO) in rat liver and brain by the short-acting MAO-A inhibitors moclobemide (Ro 11-1163 = p-chloro-N-[2-morpholinoethyl]benzamide) and brofaremine and by the short-acting MAO-13 inhibitors Ro 16-6491 (N-[2-aminoethyl]-p-chlorobenzamide) and almoxatone, administered p. o. at roughly equieffective doses 2 h before decapitation, was investigated for its reversibility under various in vitro conditions. MAO A activity in liver homogenates, inhibited by moclobemide (300 μmol/kg) to approx. 15% of control, time dependently recovered during 0.5 to 2 h of incubation at 37°C, irrespective of whether the homogenates were prepared and incubated in distilled water or Krebs-Ringer buffer (KRB). Dialysis of such homogenates for 4 h in distilled water at 37°C (but not at 13°C) led to a complete return of the MAO activity. In liver homogenates from rats pretreated with brofaremine (30 μmol/kg), dialysis for 4 h at 37°C against distilled water caused only little recovery of the MAO activity. Likewise, MAO-B inhibited by Ro 16–6491 (30 μmol/kg) to approx. 4% of control returned to almost control activity after 4 h of dialysis at 37°C, while inhibition induced by almoxatone (30 μmol/kg) was little or not reversed at all. In brain homogenates prepared in, and dialysed against, distilled water or KRB at 37°C (but not at 13°C), MAO-A inhibited by moclobemide (100–300 μmol/kg) to approx. 15% of control, partially (KRB) or almost completely (dist. water) returned to control activity after 4 h of dialysis. From rats pretreated with Ro 16–6491 (30 μmol/kg), MAO-B in brain homogenates prepared in KRB was reduced to 12% of control and returned to control value upon dialysis for 4 h in KRB at 37°C; in homogenates prepared in H2O, MAO-B was reduced to only 60% of control and completely recovered by dialysis against dest. water even at 13°C. In all of these conditions, recovery of the enzyme activity was small after brofaremine and almoxatone. Analogous results were obtained with brain slices (0.2 × 0.2 × 1.5 mm) in KRB at 37°C, whereby time dependent recovery of MAO activity during incubation was achieved, and superfusion was somewhat more effective than incubation in restoring enzyme activity. In the experiments with incubated or superfused brain slices, inhibition of MAO-A and -B by the irreversible inhibitors clorgyline and selegiline (l-deprenyl), resp., could not be reversed at all. Tyramine (0.3 mmol/l) clearly enhanced the recovery of MAO-A in KRB-prepared liver homogenates and brain slices of moclobemide-pretreated rats but not in brain slices of brofaremine- and clorgyline-pretreated rats. Thus, the reversibility of MAO inhibition in vitro could be convincingly demonstrated for moclobemide and Ro 16–6491 but not for the other novel, short-acting MAO inhibitors studied.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 43 (1965), S. 574-576 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary With a simple and sensitive method ammonia was measured in exspired air from healthy persons and patients. The values show a considerable variation, which ammounts to ±62% in healthy persons. In patients it is not possible to calculate the blood ammonia from the exspired ammonia. For diagnosis of uremia no reliable results are obtainable.
    Notes: Zusammenfassung Mit einer einfachen und empfindlichen Methode wurde Ammoniak in der Ausatmungsluft von Gesunden und Kranken gemessen. Die Meßwerte streuen erheblich, bei Gesunden ±62%. Bei Patienten kann aus dem Atemammoiak weder auf den Blutammoniak zurückgeschlossen werden, noch lassen sich bei urämischen Zuständen differentialdiagnostisch zuverlässige Hinweise erhalten.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 45 (1967), S. 314-316 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary A micromethod for the determination of ammonia in 100 µl of capillary blood is described. Trichloroacetic acid, half neutralized with sodium hydroxyde, is used for the precipitation of proteins. Thus arteficial formation of ammonia by acid hydrolysis can be avoidet almost completely. The protein-free filtrate is directly mixed with the reagents of the phenol-hypochlorit reaction. Normal values could be determinated between 47 and 115 µg/100 ml capillary blood, the mean being 81 µg/100 ml. Capillary blood determinations yielded significantly higher values than those in venous blood of the same patients. Whole-day-profiles of blood ammonia can easily be obtained by this method.
    Notes: Zusammenfassung Eine Mikromethode zur Bestimmung des Blusammoniaks wird beschrieben. Dabei wird zur Eiweißfällung Trichloressigsäure verwendet, die mit NaOH halb neutralisiert ist. Dadurch kann die artifizielle Freisetzung von Ammoniak durch Säurehydrolyse weitgehend vermieden werden. Die Normalwerte für Capillarblut lagen zwischen 47 bis 115 µg NH3-N/100 ml bei einem Mittelwert von 81 µg/100 ml. Gegenüber Venenblut wurden im Capillarblut signifikant höhere Blutammoniakspiegel gemessen. Blutammoniak-Tagesprofile lassen sich mit dieser Methode ohne besondere Belastung von Patienten und Personal leicht aufstellen.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 43 (1965), S. 43-49 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary A new method for the determination of blood ammonia concentration is described. It is based on the phenolhypochlorite reaction and characterized by a low grade of difficulty, small effort, high sensitivity and good reproducibility. The requirements and possibilities of a clinical laboratory are taken into special account. The scope and the possibility of errors are discussed in comparison with other procedures.
    Notes: Zusammenfassung Basierend auf der Phenolhypochlorit-Reaktion wird ein Verfahren zur Bestimmung der Ammoniakkonzentration im Blut angegeben. Die Methode zeichnet sich durch geringen Aufwand, niedrigen Schwierigkeitsgrad, hohe Empfindlichkeit und gute Reproduzierbarkeit aus. Die Bedingungen eines klinischen Laboratoriums wurden besonders berücksichtigt. Fehlermöglichkeiten und Anwendungsbereich werden im Vergleich zu anderen Bestimmungsverfahren diskutiert.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The first scientific objective of the HMC is to discover and observe the comet nucleus and to attempt to verify its solid nature and the general concept of the icy conglomerate model of cometary nuclei, as proposed by Whipple1 about 36 years ago. This objective involves the determination of the ...
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