Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • 1985-1989  (3)
  • 1965-1969
  • vascular permeability  (2)
  • Computerized tomography  (1)
  • 1
    ISSN: 0942-0940
    Keywords: Cerebral vasospasm ; subarachnoid haemorrhage ; vascular permeability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The time course of the blood-arterial wall barrier disruption following experimental subarachnoid haemorrhage (SAH) was studied in 24 rabbits. Animals with SAH received two successive blood injections through the cisterna magna. Horseradish peroxidase (HRP) was given intravenously 30 minutes before sacrifice to assess the integrity of the barrier. In the basilar arteries taken from animals that were sacrificed 4 days after the first SAH, HRP-reaction products were diffusely observed in the subendothelial space. Three weeks following the first SAH, permeation of HRP was still observed in half of the animals. However, in animals sacrificed 7 weeks after the first SAH, no permeation of HRP into the subendothelial space was noted. Opening of the interendothelial space seemed to be the major mechanism for HRP permeation into the subendothelial space rather than transendothelial vesicular transport. Disruption of the bloodarterial wall barrier in the major cerebral arteries following SAH may play a role in the pathogenesis of vasospasm.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    ISSN: 0942-0940
    Keywords: Subarachnoid haemorrhage ; cerebral vasospasm ; vascular permeability ; FITC-dextran
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Disruption of the blood-arterial wall barrier in the major cerebral arteries occurs following subarachnoid haemorrhage (SAH) and may be related to the pathogenesis of cerebral vasospasm. Using FITC dextrans of various sizes, the present study was undertaken to determine if the barrier disruption shortly after SAH occurs equally to various sized tracers. Forty-two Sprague-Dawley rats were divided into 5 groups. Four groups were injected with FITC-dextrans of differing molecular weights (MW): FD4 (MW=4,080), FD40 (MW=40,500), FD 70 (MW=71,400), and FD 150 (MW=156,900). One group was injected with horseradish peroxidase (HRP: MW=40,000). Each group was further divided into two subgroups: with or without SAH. SAH was induced by injecting arterial blood into the cisterna magna. To assess the integrity of the blood-arterial wall barrier by transmission electron microscope, the tracers were intravenously injected prior to sacrificing the animals. The groups without SAH showed no permeability of tracers into the subendothelial spaces of the basilar arteries. In contrast, with the exception of FD 150, FITC-dextrans (FD 4, FD 40, FD 70) were noticed in the subendothelial spaces. The distribution of FITC-dextrans in the elastic lamina was similar to that of HRP. These results suggest that barrier disruption occurs with a wide range of molecular sizes of FITC-dextrans, although there seems to be some limitation to the permeation of the larger molecules. The present study suggests that the mechanism of barrier disruption of the major cerebral arteries in the acute stage following SAH may be vesicular rather than by separation of tight junctions.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Electronic Resource
    Electronic Resource
    Springer
    International orthopaedics 10 (1986), S. 115-120 
    ISSN: 1432-5195
    Keywords: Patella ; Subluxation ; Computerized tomography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé La subluxation de la rotule peut entraîner chez les sujets jeunes des douleurs et une instabilité. Cependant, la classification, les critères du diagnostic et le traitement sont sujets à controverse. Nous avons utilisé la tomodensitométrie (TDM) pour mesurer l'importance du déplacement externe de la rotule et son inclinaison par rapport au fémur dans un groupe de malades présentant une subluxation. La déviation moyenne était de 31,4% et l'angle d'inclinaison de 31,8 degrés. Ces chiffres étaient significativement-plus élevés que ceux obtenus à partir de radiographies conventionnelles ou d'arthrographies axiales. Nous avons montré que le déplacement externe de la rotule augmente lors de la contraction volontaire du quadriceps. Lorsque le quadriceps est contracté, la déviation augmente de 27,7% sur les rotules subluxées contre 14% dans les genoux normaux. Nous avons revu 40 genoux traités par une opération de réalignement, avec un recul moyen de 27 mois. Le taux moyen de déviation externe, mesuré par TDM, s'est amélioré significativement jusqu'à des chiffres normaux, que le quadriceps soit relâché ou contracté. Les résultats, évalués selon les critères d'Insall, sont «excellents» pour 13 genoux, «bons» pour 22, «assez bons» pour 3 et «mauvais» pour 2. Le groupe des résultats satisfaisants (excellents et bons) présente une diminution du déplacement de la rotule même lors de la contraction du quadriceps, contrairement au groupe des résultats «assez bons» et «mauvais».
    Notes: Summary Subluxation of the patella may produce pain and instability in young people. However its classification, diagnosis and treatment are controversial. We have used computerized tomography (CT) to measure the amount of lateral shift of the patella and the angle of tilt to the femur in patients with subluxation. The mean lateral shift was 31.4% and the angle of tilt 31.8 degrees. These values are significantly greater than those obtained from conventional axial radiographs or in arthrographic axial views. We have obtained interesting evidence that the rate of lateral shift apparently increased on voluntary contraction of the quadriceps muscle (Q-contracted). With the quadriceps contracted, the mean rate of the lateral shift in the affected knees showed a significant increase (+ 27.7%) compared to that in normal knees (+ 14.0%). We have reviewed 40 knees treated by operative realignment with a mean follow-up of 27 months. The mean rates of lateral shift measured from CT-image in the knees before operation improved significantly to the normal range at follow-up, both with the quadriceps relaxed and contracted. The results evaluated by Insall's criteria were “excellent” in 13 knees; “good” in 22; “fair” in 3 and “poor” in 2. The satisfactory group (those with excellent and good results) revealed an improvement in lateral shift when the quadriceps was contracted, while the unsatisfactory group (fair and poor results) did not.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...