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  • 1985-1989  (3)
  • 1960-1964  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 1 (1962), S. 397-405 
    ISSN: 1432-0533
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Inoculation of polyoma virus into newborn rats can produce, a diffuse neoplastic process of the leptomeninges, which is comparable to the human primary leptomeningeal sarcomatosis and to the intracranial sarcomas produced by Rous virus in chickens and by polyoma virus in Syrian hamsters. The neuropathological features of these lesions are described. The same results were obtained by intravenous intracerebral or subcutaneous inoculation as well. The hydrocephalus can be explained by the proliferation of the tumour cells in the subarachnoïdal space. The authors point out that some hemorrhagic lesions result from the strangulation of blood vessels by neoplastic cuffs.
    Notes: Résumé L'inoculation du virus polyome chez le raton peut provoquer la formation d'un processus néoplasique diffus des leptoméninges, qui est comparable à la sarcomatose méningée primitive décrite chez l'homme et aux sarcomes intra-crâniens provoqués chez le poulet par le virus de rous et chez le hamster par le virus polyome. Les auteurs décrivent les aspects neuropathologiques de ces lésions et montrent qu'elles peuvent s'obtenir aussi bien par l'inoculation intra-veineuse, intra-cérébrale ou sous-cutanée du virus. Ils expliquent l'apparition de l'hydrocéphalie par l'invasion tumorale des espaces sous-arachnoïdiens. Ils montrent également que certaines lésions hémorragiques proviennent de la strangulation vasculaire par des manchons tumoraux.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1459
    Keywords: Cerebral embolism ; Arterial wall rupture ; Vasospasm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Previously undescribed morphological changes are reported in two cases of recent, non-septic cerebral embolism. These consisted of an arterial rupture involving the whole thickness of the wall. A direct tear by a sharp embolus seems unlikely but, as proposed by Villaret et al. in 1937, the arterial spasm may have occurred at the time of cerebral embolism. The embolic occlusion would prevent narrowing of the vascular lumen, so that focal spasm would rupture the arterial wall even at the level of a healthy and relatively thick media.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1459
    Keywords: Meningitis ; Aspergillus ; Cerebrospinal fluid
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A 30-year-old, previously healthy, non-addicted man presented with a chronic spinal meningitis complicated by arachnoiditis and spinal cord compression. Biopsy showed a chronic granulomatous leptomeningitis, in which some cells contained branching septate organisms that were immunostained with an antiserum to Aspergillus fumigatus. Precipitins to A. fumigatus were detected in cerebrospinal fluid (CSF), but not in blood, and aspergillus infection was apparently restricted to the leptomeninges. Clinically successful treatment led to the disappearance of CSF precipitins and oligoclonal bands.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neurology 235 (1988), S. 352-354 
    ISSN: 1432-1459
    Keywords: Sensory neuronopathy ; Sicca syndrome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Sensory subacute neuropathies associated with sicca syndrome without any systemic involvement have been reported rarely. A sixth case is described with what appears to be the first report of muscle and nerve biopsy findings. The histological studies revealed axonal degeneration without vasculitis in the sural nerve, and a slight denervation process and a discrete myositis in the gastrocnemius muscle, reflecting a subtle systemic disorder. The clinical course of a long-standing subacute sensory neuropathy, the biopsy-documented axonal degeneration, and the neurophysiological findings suggest involvement of the dorsal root ganglia.
    Type of Medium: Electronic Resource
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