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  • 1
    Electronic Resource
    Electronic Resource
    Annealing furnace for III-V semiconductor devices (1986)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 57 (1986), S. 206-208 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A furnace for annealing ion implantation damage in III-V semiconductors has been built and tested. Designed for research applications, the furnace can accommodate odd shapes of material up to 2 in. in diameter. Samples are loaded onto a novel cantilevered support and are not moved during the annealing operation, facilitating proximity annealing techniques. Both chambers of this dual chambered system are O-ring sealed for added safety during annealing in an arsine gas ambient. Electron mobilities between 4400 and 4600 cm2/V s at 300 K are routinely measured for 2×1017 cm−3 gallium arsenide material annealed in this sytem. The system has been used to anneal indium phosphide as well as gallium arsenide wafers.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1138970
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  • 2
    Electronic Resource
    Electronic Resource
    Structure of [P(CH3)(C6H5)3]2[{IPd[CC(=O)(OCH3)]4}2] (1989)
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 45 (1989), S. 1626-1628 
    Details
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108270189005962
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  • 3
    Electronic Resource
    Electronic Resource
    Acute and chronic effects of carbamyl glutamate on blood urea and ammonia (1985)
    Springer
    European journal of pediatrics 143 (1985), S. 196-197 
    Details
    ISSN: 1432-1076
    Keywords: Carbamyl glutamate ; Urea cycle disorders ; Hyperammonaemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Carbamyl glutamate injected into normal rats produced no change in blood urea levels. Rats fed a high-protein dict or starved for 48 h had increased blood urea. Carbamyl glutamate injection induced a further increase in the levels of urea in their blood. Also, carbamyl glutamate administered in the drinking water of normal mice produced an increase in blood urea, which was accompanied by a decrease in blood ammonia. The application of these findings to the treatment of urea cycle enzymopathies is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00442137
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  • 4
    Electronic Resource
    Electronic Resource
    Carbamyl glutamate prevents the potentiation of ammonia toxicity by sodium benzoate (1989)
    Springer
    European journal of pediatrics 148 (1989), S. 540-542 
    Details
    ISSN: 1432-1076
    Keywords: Sodium benzoate ; Hyperammonaemia ; Carbamyl derivatives
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Sodium benzoate has been recommended for the treatment of hyperammonaemia in humans. However, benzoate potentiates ammonia toxicity and reduces urea synthesis in vitro and in vivo by decreasing the intramitochondrial levels of N-acetyl glutamate. Pretreatment of mice with carbamyl glutamate, a structural analogue of N-acetyl glutamate, decreases mortality induced by ammonium acetate and sodium benzoate administration. The protective effect of carbamyl glutamate is accompanied by an increase in urea production and of carbamyl phosphate synthetase activity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00441553
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  • 5
    Electronic Resource
    Electronic Resource
    Uptake and Retention of14C-Aroclor® 1254 in the Amphipod,Gammarus tigrinus, Fed Contaminated Fungus,Fusarium oxysporum (1985)
    Springer
    Archives of environmental contamination and toxicology 14 (1985), S. 59-64 
    Details
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract Food chain transfer of polychlorinated biphenyls (PCBs) was studied by feeding contaminated fungus,Fusarium oxysporum, to the amphipod,Gammarus tigrinus, both isolated from the Hudson River. Apparent distribution coefficients (μg PCB/g dry wt. fungus // μg PCB/g medium) of 1.14–1.33 × 103 were determined when14C-Aroclor 1254 at 0.007 μg/g was added to 4-day old fungal growth for 24 hr. InG. tigrinus fed contaminated fungus, cross-gut PCB assimilation was indicated. Rapid PCB uptake occurred with a constant level achieved between 9 and 24 hr. Over a period of 144 hr, 57% of accumulated PCBs were eliminated. The results suggest that dietary uptake may contribute substantially to PCB levels inGammarus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01055762
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  • 6
    Electronic Resource
    Electronic Resource
    Effects of prolonged exposure to ammonia on fluid-phase, receptor-mediated, and adsorptive (non specific) endocytosis in cultured neuroblastoma cells (1987)
    Springer
    Histochemistry and cell biology 87 (1987), S. 445-455 
    Details
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The effect of prolonged exposure to ammonia on fluid-phase, receptor-mediated, and adsorptive (non specific) endocytosis in cultured neuroblastoma (Neuro-2a) cells were studied using fluorescein-labeled dextran, concanavalin A conjugated with fluorescein isothiocyanate, and cationized ferritin as tracers. Ammonia treatment increased the rate of endocytosis of cationized ferritin as well as the number of cell elements involved in the process. Moreover, the number of cytoplasmic components containing acid phosphatase activity was also found to increase following ammonia treatment. In contrast, flow-cytometric analyses showed that, under experimental conditions, exposure to ammonia did not alter the intralysosomal pH and had little effect on the fluid-phase and receptor-mediated endocytosis of fluorescein-labeled dextran and concanavalin-A fluorocrome, respectively.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00496816
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  • 7
    Electronic Resource
    Electronic Resource
    Über die Umkehrbarkeit der Konzentrationsvorgänge bei der Harnbildung (1933)
    Springer
    Pflügers Archiv 231 (1933), S. 280-298 
    Details
    ISSN: 1432-2013
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung In früheren Arbeiten wurde der Beweis erbracht, daß zwischen einfachen Diffusionsvorgängen und den Sekretionserscheinungen der Niere in bezug auf die Konzentrations- und die Zeitverhältnisse sowie auf die Größe der Konstanten, die bei verschiedenen Substanzen ermittelt wurden, ein enger Parallelismus besteht. Nun können Diffusionsvorgänge als physikalische Annäherung an einen Gleichgewichtszustand aufgefaßt werden, was die Umkehrbarkeit des Vorgangs bei Änderung des Gleichgewichts in sich schließt. Von diesem Gesichtspunkt aus ist in der vorliegenden Arbeit geprüft worden, ob auch in der tätigen Niere eine derartige Umkehr beobachtet werden kann, und in der Tat ließ sich dabei der Beweis für diese Erscheinung führen. Es ist damit ein weiterer Beleg dafür erbracht, daß die physikalische Diffusion bei der Bildung eines konzentrierten Harnes nicht nur ein wesentliches, sondern geradezu das führende Moment darstellt.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01754551
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  • 8
    Electronic Resource
    Electronic Resource
    Changes in auditory evoked responses and in the inhibitory action of 5-hydroxytryptophan following chronic treatment with imipramine in the rat (1988)
    Springer
    Psychopharmacology 96 (1988), S. 408-413 
    Details
    ISSN: 1432-2072
    Keywords: 5-Hydroxytryptophan ; Imipramine ; Brainstem auditory evoked response ; Middle latency auditory evoked response ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The neurophysiological effects of acute and chronic treatment with the tricyclic antidepressant drug imipramine were investigated. Brainstem (BAER) and middle latency (MLR) auditory evoked responses were monitored in the alert and immobile rat. Daily injection of imipramine (10 mg/kg, IP) for 2 weeks produced a 13% increase in the latency and a 35% reduction in the amplitude of the N17 component of the MLR. Acute imipramine treatment had no effect. There was no observable change in the BAER after either acute or chronic drug administration. Serotonergic function was assessed by studying the inhibitory effects of 5-hydroxytryptophan on the BAER and MLR. Chronic application of imipramine caused an apparent reduction of the effects of 5-hydroxytryptophan (75 mg/kg, IP) on the N17 component of the MLR. This may, however, be due to the shift in baseline latency and amplitude. Inhibition of the BAER by 5-hydroxytryptophan was unaltered by long term exposure to imipramine. Acute treatment with imipramine was without effect on the modulation of the BAER and the MLR by 5-hydroxytryptophan. These results provide evidence that chronic, as opposed to acute, administration of imipramine had an inhibitory effect on auditory processing at the level of the MLR and that this may be associated with a change in the net output of the serotonergic system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00216071
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  • 9
    Electronic Resource
    Electronic Resource
    Stage-specific mechanisms regulate the expression of the dopa decarboxylase gene during Drosophila development (1986)
    New York, NY [u.a.] : Wiley-Blackwell
    Archives of Insect Biochemistry and Physiology 3 (1986), S. 97-104 
    Details
    ISSN: 0739-4462
    Keywords: enzyme induction ; Drosophila ; steroid hormone ; 20-hydroxyecdysone ; Chemistry ; Food Science, Agricultural, Medicinal and Pharmaceutical Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: Transcripts of the dopa decarboxylase (Ddc) gene accumulate within 4 h of the administration of 20-OH-ecdysone to mature larvae of Drosophila. The increase can be explained as the sum of a direct steroid effect, independent of protein synthesis, and an indirect effect, dependent on proteins synthesized after an increase in the hormone titer. By contrast, the peaks of DDC activity in embryos, and perhaps in the first two larval instars and in imaginal discs as well, cannot be ascribed to any direct steroid effects. In fact, a decreasing hormone titer might be required before the Ddc gene can be expressed at these stages. The stage-specific differences in the molecular mechanisms regulating Ddc gene activity may be reflected in the phenotype of an activity variant, Ddc+4. Molecular studies now underway on the variant Ddc gene might help us to understand the complex multifunctional region that we believe lies upstream of the gene and regulates its expression during development.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/arch.940030711
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