ISSN:
1432-1076
Keywords:
Isolated premature thelarche
;
Pulsatile LH secretion
;
Pulsatile FSH secretion
;
Ovarian ultrasoud morphology
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract We have studied the pulsatile secretion of gonadotrophins at night and made ovarian ultrasound examinations in three girls with central precocious puberty and three with isolated premature thelarche. The three girls with precocious puberty had well-defined pulsatile secretion of LH and FSH with LH predominating, as would be expected in normal puberty. Pulsatile secretion of gonadotrophins was also seen in girls with premature thelarche but the pattern was reversed. In girls with precocious puberty, large “multicystic” ovaries and large uteri were seen on ultrasound examination, whereas girls with isolated premature thelarche had small uteri and ovaries with less than four “cysts” up to 15 mm in diameter. These data provide the key to understanding the aetiology of isolated premature thelarche.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00446063
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