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  • 1985-1989  (2)
  • Diffuse cortical enhancement  (1)
  • 9-anthryldiazomethane
  • digoxin-like immunoreactivity
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 44 (1988), S. 992-993 
    ISSN: 1420-9071
    Keywords: Endogenous digitalis-like factor ; digoxin-like immunoreactivity ; Na+,K+-ATPase inhibitor
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary We measured endogenous digitalis-like factor (EDF) in rat plasma during acute saline infusion by two different procedures. Na+,K+-ATPase inhibitory activity in the rat plasma significantly increased during saline loading (7.8±2.2 vs 2.5±0.9%, with and without acute saline loading, respectively, p〈0.05). On the other hand, the plasma digoxin-like immunoreactivity significantly decreased during acute saline loading (16.9±1.6 vs 32.0±2.8 pg digoxin equivalents/ml. with and without acute saline loading, respectively, p〈0.01). These results indicate that the major substances detected by digoxin-like immunoreactivity and direct Na+,K+-ATPase inhibitory activity are completely different, at least in rat plasma.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1920
    Keywords: Computed Tomographic Imaging ; Brain ; Hypoglycemia ; Watershed low density area ; Diffuse cortical enhancement
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A case of severe hypoglycemic coma was studied by sequential Computed Tomographic Imaging (CT) of the brain. The CT 1) was normal in the early stage, 2) subsequently showed a low density area, which was enhanced by the contrast medium, in the cerebral cortex and the boundary zone between the major cerebral arteries, and 3) revealed marked enhancement in the entire cortical region and hypodensity in the periventricular region in the late stage. These CT findings, representing the course of neural cell damage by severe hypoglycemia, are discussed from the pathophysiological viewpoint.
    Type of Medium: Electronic Resource
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