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  • 1985-1989  (2)
  • Angiotensin II  (1)
  • Automatic diagnosis  (1)
  • Ca2- current  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Molecular and cellular biochemistry 80 (1989), S. 59-72 
    ISSN: 1573-4919
    Keywords: heart cells ; aortic cells ; Ca2- current ; K+ current ; slow Na+ current ; Angiotensin II ; calcium blockers ; potassium blockers ; patch clamp
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Summary The whole-cell voltage clamp technique was used to study the slow inward currents and K+ outward currents in single heart cells of embryonic chick and in rabbit aortic cells. In single heart cells of 3-day-old chick embryo three types of slow inward Na+ currents were found. The kinetics and the pharmacology of the slow INa, were different from those of the slow Ica in older embryos. Two types of slow inward currents were found in aortic single cells of rabbit; angiotensin 11 increased the sustained type and d-cAMP and d-cGMP decreased the slow transient component. Two types of outward K+ currents were found in both aortic and heart cells. Single channel analysis demonstrated the presence of a high single K+ channel conductance in aortic cells. In cardiac and vascular smooth muscles, slow inward currents do share some pharmacological properties, although the regulation of these channels by cyclic nucleotides and several drugs seems to be different.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Medical & biological engineering & computing 27 (1989), S. 75-81 
    ISSN: 1741-0444
    Keywords: Automatic diagnosis ; Biomechanical properties ; Mechanical mobility ; MT figure ; Periodontium ; Tooth mobility
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract Tooth mobility examination is important in planning dental treatment, as it may give an indication of alveolar bone loss and the condition of the periodontal ligament. In clinical dental diagnosis a manual tooth mobility examination is useful. However, its determination of tooth mobility is subjective and depends on the skill and experience of the clinician. The authors have previously reported on a device for measuring the biomechanical properties of human periodontium using an impedance head. Using this device, the mechanical mobility of periodontium can be measured and the mechanical parameters of the periodontal physical model are obtained. Tooth mobility is defined objectively on the basis of discriminant scores of mechanical parameters, and a mobility triangle (MT) figure is drawn as a record for visual interpretation. The paper describes the validation of the mechanical mobility measurements and their interpretation using mobility parameters and a personal computer to produce a mobility triangle figure. The method is compared favourably with clinical mobility measurement. The relationship of the model to underlying pathology is tested by measurements performed on various tooth model systems.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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