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  • 1985-1989  (2)
  • Oxidant  (1)
  • Tetanus toxin  (1)
  • Botulinum toxin
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 44 (1988), S. 224-226 
    ISSN: 1420-9071
    Keywords: Tetanus toxin ; botulinum toxin ; noradrenaline ; GABA ; brain
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Rat brain homogenate was preloaded with [3H]noradrenaline or [3H]GABA and stimulated with high K+. Tetanus toxin and botulinum A neurotoxin partially prevent the evoked [3H]noradrenaline release in the same range of toxin concentrations starting below 10−10M. In contrast, release of γ-amino butyric acid (GABA) is much more sensitive to tetanus than to botulinum A toxin.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 67 (1989), S. 20-25 
    ISSN: 1432-1440
    Keywords: Oxoferin® ; Sodium chlorite ; Methaemoglobin ; Fibroblast ; Oxidant
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Oxoferin®, a preparation approved for wound treatment, has been subjected to an in vitro analysis. 1. Oxoferin® produces methaemoglobin even if diluted 500fold, and leads to additional alterations if added in high concentrations to red cells. Sodium chlorite (NaClO2, 15 mM) is equivalent to undiluted Oxoferin®. 2. Oxoferin® in fiftyfold dilution damages fibroblasts in cell culture slowly and persistently. This dilution is equieffective with a 200 µM solution of sodium chlorite. Oxoferin® and sodium chlorite also damage vascular endothelial cells. 3. The oxidation equivalent of Oxyoferin® is 12.3 mM sodium chlorite. Our data indicate that Oxoferin® may be equated essentially with aqueous sodium chlorite.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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