ISSN:
1612-1112
Keywords:
Liquid chromatography
;
Reversed-phase chromatography
;
Single-stranded oligo-DNAs
;
Effect of silica
;
Effect of the carbon content
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary A reversed-phase liquid chromatographic (RPLC) column, with which large oligodeoxynucleotides (oligo-DNAs) can be separated in well-resolved peaks, has been developed. The column contains only specially selected silica bonded with monochlorodimethyloctadecylsilane. The carbon content of the column packing is the predominant factor to achieve good results. With this column several mixtures containing different large oligo-DNAs could be separated with excellent resolution.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02311773
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