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  • 1985-1989  (3)
  • Electron microscopy  (2)
  • Polyglucosan bodies  (1)
  • POEMS syndrome
  • polyneuropathy
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Year
  • 1
    ISSN: 1432-0533
    Keywords: Alzheimer's disease ; Electron microscopy ; Substantia nigra ; Nucleus centralis superior
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In four patients with presenile Alzheimer's disease (AD) and three age-matched controls a quantitative study of neurons and neurofibrillary tangles (NFT) in the substantia nigra (SN) and nucleus centralis superior (NCS) was performed. A significant neuronal loss, similar in both nuclei, was found in AD cases, while the incidence of NFT was remarkably higher in NCS. Moreover, no significant correlation between neuronal loss and number of NFT was detected. An electron-microscopic study revealed that the subcortical NFT in NCS are made up of paired helical filaments in spite of their globose round shape.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0533
    Keywords: Axonal neuropathy ; Diabetic neuropathy ; Polyglucosan bodies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In the sural nerve of a 62-year-old woman with impaired glucose tolerance test and polyneuropathy, many intra-axonal polyglucosan bodies were observed. Polyglucosan bodies have been described in spontaneously or alloxan-diabetic rats, but are not usually observed in human diabetic neuropathy. Since intra-axonal polyglucosan bodies can occur in the sural nerve in various diseases and in aging, they are considered as non-specific changes. Their presence is probably related to a primary axonal neuropathy.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Neurological sciences 7 (1986), S. 161-163 
    ISSN: 1590-3478
    Keywords: Alzheimer disease ; Electron microscopy ; Epidemiological study
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Sommario Viene descritto lo studio neuropatologico di un caso incluso nello Studio Multicentrico Italiano sulla Demenza sulla base di dati clinici. L'esame istologico ed ultrastrutturale conferma la diagnosi di malattia di Alzheimer avvalorando quindi il protocollo clinico.
    Notes: Abstract The pathological findings in a case included in the Italian multicenter study of dementia on clinical grounds are reported. The histological and ultrastructural examination confirms the diagnosis of Alzheimer disease, evidence for the validity of the clinical protocol.
    Type of Medium: Electronic Resource
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