Electronic Resource
New York, NY
:
Wiley-Blackwell
Journal für Praktische Chemie/Chemiker-Zeitung
331 (1989), S. 835-842
ISSN:
0021-8383
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Transformation of Uridine Derivatives into Cytidines via Selective AminationThe synthesis of some 5-fluorosubstituted cytidine 2 derivatives via amination of corresponding uridine derivatives 1 is described. 5-Substituted 4-tetrazolo pyrimidinone derivatives 5 are key intermediates in the procedure. The method used is extended to other fluorinated starting materials, e.g. fluorinated uridinedinueleotides 7 or 2′-deoxy-2′-fluorouridine 9. The fluoro containing products are easily available by fluorination with elemental fluorine or hydrogene fluoride.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/prac.19893310518
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