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  • 1
    Electronic Resource
    Electronic Resource
    Effect of prostaglandin on urethral resistance and micturition (1983)
    Springer
    Urological research 11 (1983), S. 19-22 
    Details
    ISSN: 1434-0879
    Keywords: Prostaglandin ; Urethral resistance ; Micturition ; Urodynamics ; Dog experiment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of four exogenous prostaglandins, PGA1, PG802, PGE2 and PGF2α, upon the lower urinary tract was investigated in female mongrel dogs without neurogenic lesions in vivo. The urethral resistance was studied by means of a urethral pressure profile, and the bladder function by evaluating whether or not the micturition was triggered. The reduction of urethral resistance in terms of the maximum urethral closure pressure was most significant with PGE2 given intraarterially. Micturition was most frequently provoked by the intravenous administration of PG802, a derivative of PGE1. PGE series seemed to be the most potent for the evacuation of urine in female dogs.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00272704
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Insulin, S-sulphonate A and S-sulphonate B-chain receptor binding to human cultured lymphocytes (1977)
    Springer
    Diabetologia 13 (1977), S. 251-255 
    Details
    ISSN: 1432-0428
    Keywords: Insulin receptor ; cultured lymphocytes ; insulin structure function relationship ; insulin chains
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The ability of insulin and the S-sulphonate A and B-chain derivatives to bind to a receptor on cultured human lymphocytes was evaluated. A receptor site for the S-sulphonate A-chain was identified and was strongly influenced by the intact insulin molecule. S-sulphonate A-chain weakly interfered with insulin binding. S-sulphonate B-chain showed no evidence of significant binding and did not interfere with insulin or S-sulphonate A chain binding.14CO2 production from14C-1-glucose was stimulated by insulin in cultured lymphocytes and this effect was blunted by S-sulphonate A-chain. The sulphhydryl blocking agent used in the production of insulin A-chain appears to be of critical importance.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01219708
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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