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  • 1980-1984  (2)
  • 1975-1979  (5)
  • Polymer and Materials Science  (6)
  • Histamine receptor antagonists  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Sequential histamine inhalations cause increased bronchial histamine reactivity in guinea pigs: Role of platelets, thromboxanes and prostacyclin (1984)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 327 (1984), S. 148-155 
    Details
    ISSN: 1432-1912
    Keywords: Acetylsalicylic acid ; Bronchial obstruction ; Guinea pigs ; Histamine aerosol ; Histamine receptor antagonists ; Prostacyclin aerosol ; Platelets ; Thromboxane synthetase inhibitors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Groups of 6–15 guinea pigs sensitized to ovalbumin were challenged by repeated inhalations of a constant histamine dose at time 0, 10, 20, 60 and 70 min. Bronchial obstruction was measured by whole body plethysmography. The degree of bronchial obstruction increased from one challenge to the other reaching maximal values after 70 min. This increase of bronchial responsiveness to histamine after repeated histamine challenges was reduced by pretreatment with clemastine (histamine H1-receptor antagonist, 0.12 mg/kg i.p., n=7, P〈0.05) and more effectively by combined clemastine/cimetidine pretreatment (combined H1-H2-receptor antagonists, 0.12 resp. 10 mg/kg, n=7, P〈0.001); pretreatment with acetylsalicyclic acid (10 mg/kg orally) accelerated the increase of bronchial responsiveness to histamine (n=9, P〈0.01 at the second challenge), inhalation of prostacyclin (1 μg) prior to each histamine inhalation prevented the increase of bronchial histamine sensitivity totally (n=10, P〈0.001), whereas inhibition of thromboxane biosynthesis (imidazol, 10 mg/kg i.p., n=6; 4-[2-(1H-imidazol-1-yl)ethoxy]benzoic acid, 10 mg/kg i.p., n=9; imidazo(1,5-a)pyridine-5-hexanoic acid, 1 mg/kg i.p., n=8) as well as immunologic platelet depletion were ineffective in our test system. We conclude that prostacyclin inhibits the increase of bronchial responsiveness to histamine after sequential histamine inhalation challenges by a platelet independent mechanism. 1-(3-phenyl-2-propenyl)-1H-imidazol, the fourth type of thromboxane synthetase inhibitor tested (10 mg/kg i.p., n=15) showed specific effects which may be attributed to antihistamine functions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00500910
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Das Verhalten rostfreier Stahlgußlegierungen unter gleichzeitiger mechanischer und korrosiver Belastung (1980)
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 11 (1980), S. 244-258 
    Details
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Behaviour of stainless cast alloys under combined mechanical and corrosive attackIn media with 3000 mg B/1 (as boric acid, H3BO3) and varying chloride contents down to 1 mg Cl-/1 13%-Cr-steels show pitting. Under constant load cracks appear simultaneously. As can be expected, 17%-Cr-steels are more resistant and duplex ferritic austenitic steels exhibit no corrosion cracking in 3% NaCl-solution even after 10 000 hrs. Generally, corrosion resistance improves with increasing contents of ferrite forming elements. Corrosion cracks are interpreted in termes of anodic stress corrosion cracking. Notch impact bending tests with hydrogen charged specimens show that deformability is reduced.
    Notes: 13%-Cr-Stähle zeigen in Lösungen mit 3000 mg B/1 (als Borsäure, H3BO3) und unterschiedlichen Chloridgehalten Lochkorrosion bis herab zu Konzentrationen von 1 mg Cl-/1. Bei mechanischer Zugbeanspruchung treten gleichzeitig Risse auf. 17%-Cr-Stähle sind erwartungsgemäß beständiger und ferritisch-austenitische Stähle zeigen in 3% NaCl-Lösung auch im 10 000 h-Versuch keine Korrosionsrisse. Generell steigt die Beständigkeit mit zunehmendem Anteil an ferritbildenden Elementen. Die Korrosionsrisse werden als anodische Spannungsrißkorrosion interpretiert. Kerbschlagbiegeversuche mit wasserstoffbeladenen Proben ergeben eine Abnahme des Verformungsvermögens.
    Additional Material: 21 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/mawe.19800110707
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  • 3
    Electronic Resource
    Electronic Resource
    Die Inhibition von KühlkreisläufenVorgetragen am 214. DECHEMA-Kolloquium am 28. November 1974. (1975)
    Weinheim [u.a.] : Wiley-Blackwell
    Materials and Corrosion/Werkstoffe und Korrosion 26 (1975), S. 192-199 
    Details
    ISSN: 0947-5117
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: The inhibition of cooling systemsThe choice of an efficient corrosion inhibitor has to take in account the type of the cooling system, the materials used as well as the specific operating conditions, for instance - very low or very high velocities of the cooling water- heat transfer- the inhibitor may be asked to have some lubricating properties- vibrations, that can cause cavitation or fatigue corrosion- interaction between the corrosion inhibitor and other electrochemical systems of corrosion protection (cathodic protection).In numerous applications it is necessary to improve the inhibition by an addition of other effective substances (like dispersants, hardness stabilizers, mixture of inhibitors with selective protection properties).
    Notes: Die Auswahl eines Kühlwasserinhibitors richtet sich nach der Art des Kühlsystems und der darin verwendeten Werkstoffe sowie nach den spezifischen Beanspruchungen, so z. B.- extrem hohe oder niedrige Strömungsgeschwindigkeiten des Kühlmediums,- hohe Wärmebelastung der zu Kühlenden Metallwand,- Reibungsvorgänge, wobei der Inhibitor zusätzlich eine Schmierfunktion ausüben muß,- Vibrationen, die zu Kavitationserscheinungen oder zur Werkstoffermüdung führen Können,- Wechselwirkungen des Inhibitors mit anderen elektrochemischen Schutzverfahren (z. B. lokaler kathodischer Schutz von hochbeanspruchten Zonen des Kühlsystems).In zahlreichen Fällen ist es zudem notwendig, die Wirksamkeit der Inhibierung durch den Zusatz von weiteren Wirkstoffen zu unterstützen (Dispergiermittel, Härtestabilisatoren, Gemische von Inhibitoren mit selektiver Schutzwirkung).
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/maco.19750260304
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  • 4
    Electronic Resource
    Electronic Resource
    Prüfung und Auswahl von KavitationsinhibitorenVortrag, gehalten an der Università di Ferrara anläßlich des 4. Europäischen Symposiums über Korrosionsinhibitoren, September 1975. (1976)
    Weinheim [u.a.] : Wiley-Blackwell
    Materials and Corrosion/Werkstoffe und Korrosion 27 (1976), S. 425-431 
    Details
    ISSN: 0947-5117
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Testing and Selecting Cavitation InhibitorsAn investigation has been made into possibility of using electrochemical procedures as well as the gravimetrical method for testing cavitation inhibitors. The relation between the structure of the inhibitor, the nature and form of the cavitation attack and the mechanism of destruction was also examined. This work was performed with a group of conventional cooling water inhibitors and some pyridine compounds.It was shown that electrochemical investigations are less suitable for enabling inhibitors to be selected for high cavitation intensities, because electrochemical losses amount to only a relatively small part of the total loss of material. Nevertheless they are indispensable as a supplement to magnetostrictive investigations for appraising the overall performance of an inhibitor, because it has been found that a good cavitation inhibitor does not always achieve the same success against electrochemical corrosion.Furthermore it was demonstrated that interface inhibitors generally yield better results than membrane inhibitors or passivators. The protection afforded by interface inhibitors depends on their structure, the chain length and in the case of the pyridine components investigated the nature and position of the substituents in the pyridine ring.
    Notes: Es wurde untersucht, ob für die Erprobung von Kavitationsinhibitoren neben der gravimetrischen Methode auch elektrochemische Prüfverfahren eingesetzt werden können. Es wurde ferner der Zusammenhang zwischen Struktur des Inhibitors, Art und Form des Kavitationsangriffes und Mechanismus der Zerstörung untersucht. Diese Arbeit wurde mit einer Gruppe herkömmlicher Kühlwasserinhibitoren sowie mit einigen Pyridinverbindungen durchgeführt.Wie es sich zeigte, sind elektrochemische Untersuchungen weniger geeignet, eine Inhibitorauswahl bei hohen Kavitationsintensitäten zu ermöglichen, da die elektrochemische Metallauflösung nur einen relativ kleinen Teil des gesamten Abtrags ausmacht. Sie sind aber als Ergänzung zu magnetostriktiven Untersuchungen für die Beurteilung des Gesamtverhaltens eines Inhibitors unbedingt notwendig, da es sich gezeigt hat, daß nicht immer ein guter Kavitationsinhibitor mit demselben Erfolg gegen elektrochemische Korrosion eingesetzt werden kann.Wie sich außerdem herausstellte, liefern Grenzflächeninhibitoren in der Norm bessere Resultate als Membraneninhibitoren oder Passivinhibitoren. Bei den Grenzflächeninhibitoren ist die Schutzwirkung von der Struktur des Inhibitors abhängig, wobei insbesondere Kettenlänge und - bei den untersuchten Pyridinverbindungen - Art und Stellung der Substituenten eine wichtige Rolle spielen.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/maco.19760270606
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  • 5
    Electronic Resource
    Electronic Resource
    Die Inhibierung der Korrosion in industriellen Kühlsystemen (1979)
    Weinheim [u.a.] : Wiley-Blackwell
    Materials and Corrosion/Werkstoffe und Korrosion 30 (1979), S. 713-722 
    Details
    ISSN: 0947-5117
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/maco.19790301007
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  • 6
    Electronic Resource
    Electronic Resource
    The restoration of articular surfaces overlying replamineform porous biomaterialsPresented in part at the Sixth International Biomaterials Symposium, Clemson University, Clemson, South Carolina, April, 1974. (1977)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 11 (1977), S. 165-178 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Replamineform porous implants (4 mm × 4 mm diameter) were placed into full-thickness cartilage and bone defects of the weight-bearing surface of the lateral femoral condyles of adult male white rabbits. These were analyzed at 1 day, 1 week, 6 weeks, 3 months, and 6 months for (1) ingrowth of tissue within the implants and (2) restoration of the articular surface overlying them. Appropriate unfilled, but similar, control defects were also studied.Mineralized bone was seen within the substance of both the TiO2 and hydroxyapatite implants at 1 week; this extremely rapid response was present in every specimen studied and was not seen with αAl2O3 or control animals. With the passage of time, maturation of this bone ingrowth occurred so that by 3 months, they were all incorportated into the surrounding bone.Only the hydroxyapatite implants showed consistent regenerative healing of hyaline articular cartilage from the margins of the defects with the passage of time; this occurred whenever the subchondral bone adjacent to the defect proliferated in a “creeping” fashion over the articular aspect of the implant, and the undamaged cartilage then followed it. Fibrocartilage, and not hyaline cartilage, formed the articular surface over the TiO2 and αAl2O3 implants and in the controls.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820110203
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  • 7
    Electronic Resource
    Electronic Resource
    A multichannel electro-optical detector for rapid acquisition of X-ray photoelectron spectroscopy data (1979)
    Chichester [u.a.] : Wiley-Blackwell
    Surface and Interface Analysis 1 (1979), S. 45-46 
    Details
    ISSN: 0142-2421
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Notes: An electro-optical detector easily adaptable to any hemispherical sector photoelectron spectrometer is described. The detector consists of a channel plate electron multiplier array, phosphor screen, silicon intensified target vidicon an optical multichannel analyzer control unit. Data collection rates are improved by more than two orders of magnitude over conventional single channel detectors.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/sia.740010109
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