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  • 1980-1984  (4)
  • 1975-1979  (1)
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Year
  • 1
    Electronic Resource
    Electronic Resource
    Animal models of infra-oral chemical carcinogenesis: A review (1981)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral pathology & medicine 10 (1981), S. 0 
    Details
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract Early attempts to induce malignant oral tumours were largely unsuccessful, us the oral mucosa is considerably more resistant to the actions of chemical carcinogens than skin. The first consistent success came when strong carcinogens were applied to the hamster cheek pouch. This model remains the most popular for studies of intra-oral carcinogenesis and is discussed at length. The advantages and disadvantages are critically reviewed. The models of intra-oral carcinogenesis in extra-pouch sites in the hamster, mouse, rat and nonhuman primates arc considered. The possible reasons for the relative resistance of oral mucosa to chemical carcinogens are discussed, particularly in relation to portals of entry and saliva. Finally, the relative merits of the more popular models of intra-oral carcinogenesis are briefly discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0714.1981.tb01259.x
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Angiolymphoid hyperplasia with eosinophilia (1979)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral pathology & medicine 8 (1979), S. 0 
    Details
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract Angiolymphoid hyperplasia with eosinophilia is a recently recognized lesion of skin consisting of atypical vascular proliferation and variable inflammatory cell infiltration. A case is described here of a similar lesion presenting as an intraoral swelling. In addition to showing the histological features generally associated with angiolymphoid hyperplasia with eosinophilia, the present case exhibited striking smooth muscle proliferation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0714.1979.tb01629.x
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Paget's disease of bone with particular reference to dentistry (1981)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral pathology & medicine 10 (1981), S. 0 
    Details
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract Paget's disease of bone (osteitis deformans) is a relatively common disorder of uncertain aetiology. It is characterised by abnormal resorption and apposition of osseous tissue in one or more bones of the skeleton. This paper is a review of Paget's disease with particular reference to dentistry. The prevalence, aetiology, clinical features, radiography, histopathology, biochemistry, oral and dental manifestations, complications and treatment are discussed. One hundred and fifty-two reported cases of Paget's disease of the jaws have been analysed. The upper jaw was more frequently involved than the lower jaw in the ratio of more than 2:1. This survey shows a higher prevalence of Paget's disease in the mandible than previously recorded.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0714.1981.tb01270.x
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    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Hamster tongue carcinogenesis I. Characteristics of the experimental model (1981)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral pathology & medicine 10 (1981), S. 0 
    Details
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Thrice weekly applications of DMBA to hamster ventral lingual mucosa, preceded by scratching with a barbed broach, led to tumor development in over 75% of the animals by 28 weeks. Macroscopic ulceration did not appear to be a necessary precursor of epithelial malignancy in this model. Tumors were preceded by a phase resembling human leukoplakia. In addition to developing tumors in the treated area, 60% of the hamsters developed tumors in the floor of the mouth or the area of mucosa on either side of the median lingual fraenum.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0714.1981.tb01284.x
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Hamster tongue carcinogenesis II. Quantitative morphologic aspects of preneoplastic epithelium (1981)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral pathology & medicine 10 (1981), S. 0 
    Details
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Stereological techniques have been used to quantify some morphologic aspects of non-neoplastic and preneoplastic hyperplasia in hamster tongue. Scratching hamster ventral lingual mucosa and applying acetone thrice weekly resulted in moderate epithelial hyperplasia in biopsy material removed at 16 weeks. There was a significant increase in the number of progenitor cells per defined histologic field and a striking increase in the number of progenitor cells related to each unit of surface length. There was a small but significant increase in basement membrane length. In the experimental group in which the ventral lingual mucosa was scratched and painted with 0.5% DMBA in acetone there was pronounced epithelial hyperplasia with increases in the thickness of the progenitor, maturation and keratinized compartments. Progenitor cells showed hyperplasia and hypertrophy. The number of progenitor rolls related to each unit of surface length was significantly greater than normal or control values. There was a significant increase in the basement membrane length per field, reflecting an increased folding and prominence of the rete ridges.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0714.1981.tb01285.x
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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