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  • 1
    Electronic Resource
    Electronic Resource
    Langerhans cell histiocytosis presenting as bilateral eosinophilic granulomata in the molar region of the mandible A case report (1998)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of clinical periodontology 25 (1998), S. 0 
    Details
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract. Eosinophilic granuloma represents one of a triad of lesions encompassing a disease under the generic name, histiocytosis X or Langerhans cell histiocytosis. Localised eosinophilic granuloma, muitifocal eosinophilic granuloma, Hand-Schüller-Christian disease, and the most malignant form of histiocytosis, Letterer-Siwe disease, can all present as destructive bony lesions of the jaws. The present case was a 30-year-old man who presented with almost total destruction of the periodontal support to the left and right mandibular, 1st and 2nd molars. Whereas the radiographic features were typical of eosinophilic granuloma, the clinical appearance and mirror image presentation were unusual.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-051X.1998.tb02451.x
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  • 2
    Electronic Resource
    Electronic Resource
    Oral cancer development in patients with oral lichen planus (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral pathology & medicine 22 (1993), S. 0 
    Details
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: There has been considerable controversy as to whether oral lichen planus (LP) has a premalignant potential. This study retrospectively examined the records of 241 British patients with histologically confirmed LP seen during the 10-year period 1982–92. Nine patients (3.7%) were known to have developed well-differentiated invasive carcinoma or carcinoma in situ in an area of LP. Most carcinomas at presentation were in areas of atrophic and/or erosive LP, 6 were in patients older than 65 years, and 6 were on the tongue. The results support a small but clinically important premalignant potential for LP.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0714.1993.tb00134.x
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  • 3
    Electronic Resource
    Electronic Resource
    Hamster tongue carcinogenesis II. Quantitative morphologic aspects of preneoplastic epithelium (1981)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral pathology & medicine 10 (1981), S. 0 
    Details
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Stereological techniques have been used to quantify some morphologic aspects of non-neoplastic and preneoplastic hyperplasia in hamster tongue. Scratching hamster ventral lingual mucosa and applying acetone thrice weekly resulted in moderate epithelial hyperplasia in biopsy material removed at 16 weeks. There was a significant increase in the number of progenitor cells per defined histologic field and a striking increase in the number of progenitor cells related to each unit of surface length. There was a small but significant increase in basement membrane length. In the experimental group in which the ventral lingual mucosa was scratched and painted with 0.5% DMBA in acetone there was pronounced epithelial hyperplasia with increases in the thickness of the progenitor, maturation and keratinized compartments. Progenitor cells showed hyperplasia and hypertrophy. The number of progenitor rolls related to each unit of surface length was significantly greater than normal or control values. There was a significant increase in the basement membrane length per field, reflecting an increased folding and prominence of the rete ridges.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0714.1981.tb01285.x
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  • 4
    Electronic Resource
    Electronic Resource
    Angiolymphoid hyperplasia with eosinophilia (1979)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral pathology & medicine 8 (1979), S. 0 
    Details
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract Angiolymphoid hyperplasia with eosinophilia is a recently recognized lesion of skin consisting of atypical vascular proliferation and variable inflammatory cell infiltration. A case is described here of a similar lesion presenting as an intraoral swelling. In addition to showing the histological features generally associated with angiolymphoid hyperplasia with eosinophilia, the present case exhibited striking smooth muscle proliferation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0714.1979.tb01629.x
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  • 5
    Electronic Resource
    Electronic Resource
    Paget's disease of bone with particular reference to dentistry (1981)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral pathology & medicine 10 (1981), S. 0 
    Details
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract Paget's disease of bone (osteitis deformans) is a relatively common disorder of uncertain aetiology. It is characterised by abnormal resorption and apposition of osseous tissue in one or more bones of the skeleton. This paper is a review of Paget's disease with particular reference to dentistry. The prevalence, aetiology, clinical features, radiography, histopathology, biochemistry, oral and dental manifestations, complications and treatment are discussed. One hundred and fifty-two reported cases of Paget's disease of the jaws have been analysed. The upper jaw was more frequently involved than the lower jaw in the ratio of more than 2:1. This survey shows a higher prevalence of Paget's disease in the mandible than previously recorded.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0714.1981.tb01270.x
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  • 6
    Electronic Resource
    Electronic Resource
    Hamster tongue carcinogenesis I. Characteristics of the experimental model (1981)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral pathology & medicine 10 (1981), S. 0 
    Details
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Thrice weekly applications of DMBA to hamster ventral lingual mucosa, preceded by scratching with a barbed broach, led to tumor development in over 75% of the animals by 28 weeks. Macroscopic ulceration did not appear to be a necessary precursor of epithelial malignancy in this model. Tumors were preceded by a phase resembling human leukoplakia. In addition to developing tumors in the treated area, 60% of the hamsters developed tumors in the floor of the mouth or the area of mucosa on either side of the median lingual fraenum.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0714.1981.tb01284.x
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  • 7
    Electronic Resource
    Electronic Resource
    Animal models of infra-oral chemical carcinogenesis: A review (1981)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral pathology & medicine 10 (1981), S. 0 
    Details
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract Early attempts to induce malignant oral tumours were largely unsuccessful, us the oral mucosa is considerably more resistant to the actions of chemical carcinogens than skin. The first consistent success came when strong carcinogens were applied to the hamster cheek pouch. This model remains the most popular for studies of intra-oral carcinogenesis and is discussed at length. The advantages and disadvantages are critically reviewed. The models of intra-oral carcinogenesis in extra-pouch sites in the hamster, mouse, rat and nonhuman primates arc considered. The possible reasons for the relative resistance of oral mucosa to chemical carcinogens are discussed, particularly in relation to portals of entry and saliva. Finally, the relative merits of the more popular models of intra-oral carcinogenesis are briefly discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0714.1981.tb01259.x
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  • 8
    Electronic Resource
    Electronic Resource
    Tumours of the minor (oropharyngeal) salivary glands: a demographic study of 336 cases (1985)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral pathology & medicine 14 (1985), S. 0 
    Details
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: There arc 2410 primary epithelial salivary gland tumours in the files of the British Salivary Gland Tumour Panel. Of these tumours, 336 (14%) involved the minor (oropharyngeal) salivary glands, and these were studied m the present investigation Individual tumours were diagnosed according to the W H O Classification The percentage of malignant or potentially malignant tumours (46%) was much higher than in major glands (18%), and in some of the less common intraoral sites all the tumours were malignant. The principal sites were the palate (54%), lips (21%) and buccal mucosa (11%), and, in these sites, pleomorphic adenoma was the most common tumour Monomorphic adenomas accounted for 6% of palatal tumours, hut 30% of lip salivary gland tumours. The most common malignant tumour was the adenoid cystic carcinoma The results arc compared with several other large surveys and with tumours of major salivary glands.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0714.1985.tb00522.x
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  • 9
    Electronic Resource
    Electronic Resource
    Preliminary characterization and distribution of vicia villosa binding cells in human tonsils (1989)
    Springer
    Virchows Archiv 414 (1989), S. 173-178 
    Details
    ISSN: 1432-2307
    Keywords: Tonsils ; Vicia villosa lectin ; Lymphocyte subpopulations ; Contrasuppressor cells ; Double labelling
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The lectin Vicia villosa (VV) has been used for the separation of human and murine contrasuppressor T cells. These cells were characterized in cryostat sections of human palatine tonsils by double staining with VV lectin and monoclonal antibodies to macrophages, lymphocytes and their subsets using a fluorescein-rhodamine technique. VV lectin had an affinity for the CD8+ subset of lymphocytes and for a subset of macrophages within the germinal centre. The number and distribution of VV lectin binding cells was studied in paraffin sections of formalin fixed tonsils by the avidin-biotin-peroxidase technique. Positive cells in the germinal centres, mantle, interfollicular zones and fibrous connective tissue septa were quantified using an image analyser. These were found in greatest density in the interfollicular zone, correlating with the known distribution of T cells in human palatine tonsils. The binding of VV lectin to a subset of macrophages appears not to have previously been described nor have VV lectin binding CD8+ lymphocytes been demonstrated in sections of human tissues.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00718597
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