ISSN:
1434-9949
Keywords:
IgG-Rheumatoid factor
;
IgA-Rheumatoid factor
;
Enzyme Immunoassay
;
Rheumatic Diseases
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The immunoglobulin class of rheumatoid factor (RF) in sera and synovial fluids of patients with rheumatic diseases was measured by a solid-phase enzyme immunoassay. IgG-RF was frequently found in seronegative sera as well as in seropositive sera of rheumatic patients. Titers of IgG-RF were higher in the active phase than in the inactive phase of SLE and showed a correlation to the levels of hypocomplementemia and circulating immune complexes in SLE sera. Titers of IgA-RF were likewise higher in the active-phase of SLE with a correlation to titers of circulating immune complexes. IgA-RF was also found frequently in sera of patients with Sjögren's syndrome.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02032171
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