Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    A comparative study of the effects of aspirin and paracetamol (acetaminophen) on platelet aggregation and bleeding time (1984)
    Springer
    European journal of clinical pharmacology 26 (1984), S. 567-571 
    Details
    ISSN: 1432-1041
    Keywords: aspirin ; paracetamol ; plasma aspirin esterase activity ; bleeding time ; platelet aggregation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary In a double blind, randomised trial, the effects of 1 g aspirin and 1 g paracetamol were compared on bleeding time and platelet aggregation in 40 volunteers (20 females). Also investigated was the relationship between plasma aspirin esterase activity and both bleeding time and platelet aggregation after aspirin. Following 1 g aspirin there was a significant increase in bleeding time at 24 h (p〈0.01). A significant reduction (P〈0.01) in platelet aggregation with collagen was observed at 1, 6 and 24 h after aspirin, but no significant reduction (P〉0.05) was observed with ADP. Paracetamol had no effect on bleeding time or platelet aggregation. Plasma aspirin esterase activity ranged from 0.26–0.6 µmol/ml/min. A significant negative correlation (R=−0.55, P〈0.001) was observed between percentage increase in bleeding time (24 h) and plasma aspirin esterase activity. Further significant correlations were observed between plasma aspirin esterase activity and change in platelet aggregation with collagen at 1 h (R=0.68, P〈0.001), 6 h (R=−0.73, P〈0.001) and 24 h (R=−0.67, P〈0.001). These results suggest that it might be possible to predict an individual's haemostatic response to aspirin from knowledge of their plasma aspirin esterase activity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00543486
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Thermal degradation of polymers. Part III. Vacuum pyrolysis of poly(m-aminostyrene); the products volatile at pyrolysis temperature which are liquid or gaseous at room temperaturePaper presented at Thermal Analysis Group of Society of Analytical Chemistry Burlington House, London, on November 13th, 1968. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 13 (1969), S. 2033-2043 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: The products obtained on degradation of poly(m-aminostyrene) in vacuo are described. The effect of molecular weight and pyrolysis temperature are discussed and the behavior of poly(m-aminostyrene) compared with that of polystyrene. Quantitative analytical methods using ultra-violet spectroscopy and gas liquid chromatography are described for m-aminostyrene and m-toluidine. The possible mechanisms of degradation to yield the products are discussed.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1969.070131001
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Structure of the deoxytetranucleotide d-pApTpApT and a sequence-dependent model for poly(dA-dT)Supplementary material on observed and calculated structure factors for d-pApTpApT is available from the authors. (1982)
    New York : Wiley-Blackwell
    Biopolymers 21 (1982), S. 513-533 
    Details
    ISSN: 0006-3525
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The x-ray structure of the hydrated ammonium salt of the deoxytetranucleotide d-pApTpApT was determined by Patterson and direct methods at a resolution of 1 Å. The crystal structure contains right-handed double-helical segments formed by complementary Watson-Crick-type hydrogen bonding between the adenine and thymine bases of neighboring molecules. The minihelix contains two base pairs. The chains are antiparallel. The A-T and T-A sequences have different phosphodiester conformations. The deoxyribose-pucker and the sugar-base orientation alternate along the chain depending on the nature of the base (3′-endo for purine and 2′-endo for pyrimidine). The extended structure is stabilized by base-base, base-sugar, and hydrogen-bond interactions. The minihelix of two base pairs provides starting coordinates for model-building studies of the dA-dT polymer. A B-DNA-type polymer structure is described, which has sequence-dependent alternations of both the deoxyribose pucker and the phosphate diester bridge conformation. Such sequence-dependent DNA structures, if present locally in regions such as operator sequences, could facilitate sequence-specific interactions. The crystal study also suggests possible geometrical parameters for the replication fork.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bip.360210304
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Thermal degradation of polymers. part IV. Vacuum pyrolysis of poly(m-aminostyrene). The residue and the fraction volatile at pyrolysis temperature involatile at room temperature (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 13 (1969), S. 1555-1567 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: The effect of the extent of degradation of poly(m-aminostyrene) on the quantity and composition of the residue and the effect of pyrolysis temperature on the fraction volatile at pyrolysis temperature are discussed. The behavior of poly(m-aminostyrene) is compared to that of polystyrene; a significant difference has been found for the behavior of the residue from poly(m-aminostyrene), which is ascribed to a crosslinking reaction involving the amino substituent. Mechanisms to acount for the observed products of degradation have been suggested and are discussed. Relative thermal stability studies have also been made and compared with results from polystyrene.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1969.070130718
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Thermal degradation of polymers. II further thermogravimetric and differential thermal analysis studies of atactic poly(m-aminostyrene) homopolymers, copolymers, and related polymers (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 13 (1969), S. 401-415 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Thermogravimetric and differential thermal analysis have been employed to study the effect on the thermal degradation pattern in static air of the molecular weight of poly(m-aminostyrene) homopolymers and copolymers with styrene. Related substituted styrene polymers and copolymers with styrene have also been studied in order to assess the effect of introduction of amino, substituted amino, and hydroxy groupings into a polystyrene main chain. The effect of these groupings on the thermal stability of the polymers as compared with polystyrene suggests that the inherent antioxidant characteristics of the subtituent grouping plays the major role in stabilization. A molecular weight effect has been shown to be operative for m-aminostyrene, p-N,N-dimethylaminostyrene, and m-hydroxystyrene polymers. This manifests itself in terms of different thermograms rather than by significantly influencing the procedural decomposition temperatures, although a trend is seen.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1969.070130301
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...