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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Analytical chemistry 56 (1984), S. 160-163 
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Inorganic chemistry 21 (1982), S. 130-135 
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Meteorology and atmospheric physics 32 (1983), S. 161-185 
    ISSN: 1436-5065
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography , Physics
    Description / Table of Contents: Zusammenfassung Bei der Modellierung mesoskaliger Küstenklimaeffete sind wegen des Übergangs Land-Meer, repräsentiert durch die Rauhigkeitslangez 0 =z 0 (x, y) und die WärmekapazitätC 0 =C 0 (x,y), und des verstärkten Einflusses der Feuchte ausgeprägte Inhomogenitaten zu berücksichtigen, welche die meteorologischen Verhältnisse signifikant mitgestalten. Mit Hilfe eines dreidimensionalen numerischen Modells werden in der vorliegenden Arbeit die Auswirkungen solcher horizontaler Inhomogenitaten auf Struktur und Variation der Grenzschicht in der Küstenregion studiert, Bowie die Entstehung von Advektionsnebel unter dem Einfluss unterschiedlicher geostrophischer Winde untersucht. Die Modifizierung der Windstärke und Windrichtung in ihrer Abhängigkeit von der Rauhigkeitslange und der unterschiedlichen thermischen Schichtung Bowie zwei Beispiele von Advektionsnebelbildung bei unterschiedlichem geostrophischem Wind werden als Ergebnisse vorgestellt.
    Notes: Summary When modelling mesoscale effects in the coastal climate we have to account for the significant influence of humidity and for the land-sea contrast which is represented by the roughness lengthz 0 =z 0(x, y) and the heat capacityC 0 =C 0 (x, y). This brings about strong horizontal inhomogenities which affect the meteorological situation significantly. The effects of these inhomogenities on the structure and variation of the boundary layer in the coastal region are studied by use of a three-dimensional numerical model; the formation process of advective fog in connection with different geostrophic winds is also investigated. As main results we present 1) the modifications of wind velocity and wind direction as a function of the roughness distribution and different thermal stratifications and 2) two simulations of advective fog formation assuming different geostrophic wind values in each example.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1570-7458
    Keywords: Pteromalidae ; Dinarmus vagabundus ; Bruchidae ; Callosobruchus maculatus ; Ectoparasite grégaire ; Rapport des sexes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Summary The effect of the density of ♀ parasitoids upon their hosts (Callosobruchus maculatus) was studied by the sex-ratio of the offspring of one, two or three ♀ parasitoids, each put in an experimental box. Each group of females received daily four seeds of Vigna radiata infested by the host; each seed contained on average two host larvae of 18–20 days old. After 24 hours with the parasites, the 4 seeds were removed to separate containers so the parasites emerging from each could be examined. The number of larvae/host increases when two or three ♀ parasitoids (D. vagabundus) attack the same host. The average number of offspring (daughters and sons) during the first 20 days of the reproductive activity rises significantly with the number of ovipositing ♀♀. When the density of ovipositing ♀♀ is increased from one to three, the sex-ratio of the offspring ♂/♀ changes towads the value one, with the proportion of emergent sons increasing more quickly than that of the daughters. The increase of the parasitoid numbers in one host causes a modification of the sexratio, favouring ♂ ♂. In our experimental conditions we find 1) significant increase in emergent daughters in the presence of three ovipositing ♀♀, 2) elevation in number of emergent sons as soon as there is more than one ovipositing ♀. In the presence of only one ovipositing ♀, an average of one ♂ emerges per host, this average production of 0.5 increases in the presence of two ovipositing ♀♀ and is doubled in the presence of three ♀.
    Notes: Abstract Lorsque 2 femelles ou 3 femelles de l'ectoparasite D. vagabundus parasitent conjointement un même lot d'hôtes l'intensité du grégarisme larvaire s'accroît par rapport à celui observé en présence d'une seule femelle pondeuse. Cela se traduit par une augmentation significative du nombre moyen de descendants des 2 sexes mais la production moyenne en fils est toujours très inférieure à celle des filles. Cependant, lorsque la densité de femelles pondeuses passe de 1 à 3, le rapport des sexes mâles/femelles des descendants évolue vers l'unité traduisant une augmentation plus rapide de l'effectif des fils que des filles.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Cancer immunology immunotherapy 11 (1981), S. 217-224 
    ISSN: 1432-0851
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Two BCG vaccine preparations were prepared following different production methods. Immuno-BCG Pasteur F was produced by surface culture on Sauton medium; BCG-RIV was a homogenous stirred deep culture. The antitumor effects of the two BCG vaccines were investigated on the Lewis lung carcinoma (3LL) in C57Bl/6 mice. A direct relationship exists in this tumor model between the log10 dose of single-cell suspension inoculated subcutaneously in the hind footpad of mice and the onset and the degree of local tumor growth and the time of death, which is directly related to the lung metastases. No significant difference from control mice was observed in the two groups of BCG-immunized mice when 3LL tumor cells were injected 2 weeks after BCG immunization. When varying numbers of viable units of the two BCG vaccines were injected together with 105 tumor cells in separate groups of normal mice, a dose-dependent local reaction was observed with Immuno-BCG Pasteur F, which was associated with a delay in the onset and development of tumor growth and an increase in the mean survival time. The local inflammatory reaction produced with BCG-RIV was of lower magnitude, and only the highest concentration (1.8×106 viable units) led to some delay in tumor occurrence and mortality. The antitumor effect of a specific local delayed-type hypersensitivity (DTH) elicited by varying amounts of the two BCG preparations injected together with 105 tumor cells in separate groups of normal or BCG-immunized mice showed that the challenge injection of Immuno-BCG Pasteur F was in all cases more effective than the BCG-RIV, but these two vaccines were more effective in BCG-RIV-immunized mice than in Immuno-BCG F Pasteur-immunized mice. When the same number of viable units within each BCG vaccine was used as a criterion of comparison, Immuno-BCG Pasteur F produced a higher specific and nonspecific local inflammatory reaction (which was associated with a local antitumor effect) than BCG-RIV. But within 2 weeks, the latter was much better able to sensitize the mice to mycobacterial antigens. This was confirmed by the evaluation of local granuloma formation and tuberculin hypersensitivity. BCG vaccines prepared as surface-grown pellets and mechanically dispersed always sensitized mice to a lesser degree and after a much longer period of time than did the well-dispersed deep-cultured vaccine.
    Type of Medium: Electronic Resource
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  • 6
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    Unknown
    Paris : Periodicals Archive Online (PAO)
    Revue française de sociologie. 25:4 (1984:oct./déc.) 636 
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  • 7
    facet.materialart.
    Unknown
    Roma : Periodicals Archive Online (PAO)
    Archivum historicum Societatis Iesu. 50 (1981) 76-120 
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  • 8
    ISSN: 1432-0428
    Keywords: Type I diabetes ; exercise ; open-loop insulin infusion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary To assess the risk and possible mechanisms of hypoglycaemia during moderate exercise in Type I (insulin-dependent) diabetic patients receiving constant insulin infusion, five insulin-dependent male diabetic patients were exercised 18 h after their last meal and 30 h after their last injection of intermediate acting insulin. Intravenous insulin was initially delivered via a closed-loop infusion system programmed to lower mean blood glucose from 11.3 ± 1.8 to 4.8 ± 0.4 mmol/l over approximately 3.5 h. Blood glucose was then maintained at this level for 4 h. At this time, the closed-loop infusion was discontinued and replaced by an open-loop system. The average amount of insulin infused per min during the 4 h normoglycaemic closed-loop period was calculated and this amount was infused at a constant rate during both a 30 min period of exercise on a bicycle ergometer (approximately 65% maximum oxygen uptake) and a 30 min rest period which followed. Five nondiabetic males served as control subjects. Despite significantly higher free insulin concentrations (p 〈 0.05) and identical preexercise blood glucose concentrations, blood glucose rose during exercise only in the diabetic group (0.5 ± 0.2 mmol/l; p 〈 0.01). Changes in the serum concentrations of lactate, glycerol, glucagon, cortisol, non-esterified fatty acids and growth hormone were similar in the two groups and did not account for the increment of blood glucose in the diabetic patients. Beta-hydroxybutyrate concentrations were, however, higher in the diabetic patients at the onset of exercise (p 〈 0.01) and decreased significantly more than the control subjects during exercise. We conclude that exercise under these conditions in diabetic patients is not attended by hypoglycaemia.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-0843
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Escalating doses of DDMP (metoprine) (15–280 mg/m2) were administered as single oral doses 24 h before a fixed leucovorin (CF) rescue (15 mg IM every 6 h for 72 h). CNS toxicity was dose-limiting and cumulative when the drug was given more frequently than at 3-week intervals. DDMP has a very long half-life (150 h) and is extensively bound to serum proteins (88%). It diffuses into the CSF and concentrates in brain tumours and normal brain tissue (brainserum ratio 3.8–5.3). DDMP is a potentially useful drug against brain tumors. Tumor regressions were seen in two patients with epidermoid carcinomas.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The immunopotentiating action of BCG was evaluated in rabies. The maximum enhancing effect on delayed type hypersensitivity (DTH) was obtained 14 days after rabies immunization when different BCG vaccination schedules were tested in mice. A stable form of specific sensitization to rabies antigen under the modulation of BCG pretreatment was obtained. High concentrations of rabies antigen were found to be inhibitory for the DTH reaction. Levels of protection were evaluated in rabies vaccination after BCG modulation. One single injection of rabies vaccine in BCG pretreated mice was as effective as two injections of rabies vaccine in normal mice. However, in the latter, increase of protection was correlated with the levels of neutralizing antibody. On the other hand, in BCG pretreated mice, protection was not associated with a significant increase of antibody. Pretreatment with BCG alone influenced the outcome of fixed rabies as well as street rabies by enhancing the natural resistance to rabies infection.
    Type of Medium: Electronic Resource
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