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  • 1
    ISSN: 1432-1335
    Keywords: Inbred rabbits ; Herpesvirus saimiri ; Malignant lymphoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Four young strain III/J rabbits of both sexes were inoculated with a single dose of prototype partially purified Herpesvirus saimiri (HVS) via IV and IM routes. All inoculated animals had enlarged lymph nodes, and significant levels of antibodies to HVS early, late, and membrane antigens were detectable during the infection. The animals died or were killed and HVS was isolated from the peripheral blood mononuclear cells and the various lymph nodes but not from the kidney. Microscopic examination showed that these animals had poorly differentiated lymphomas. The response of mononuclear cells to PHA from peripheral blood of infected animals showed depressed cell mediated immune responses. Humoral and cellular immunity responses during tumorigenesis were comparable to those reported in nonhuman primates with HVS-induced tumors. Thus, the inbred strain III/J appears to be an inexpensve suitable model for studies of oncogenic herpesvirus-induced cancers.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Plant and soil 81 (1984), S. 165-176 
    ISSN: 1573-5036
    Keywords: Avocado ; Ca ; Mn ; Oxisol ; P ; pH ; Phytophthora root rot ; Soil water
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Summary This experiment employed a factorial design combining 4 soil pH levels, 3 soil moisture levels, with and without the addition ofPhytophthora cinnamomi to the soil to evaluate the conditions that lead to Phytophthora root rot of avocado. An inverse relation between soil pH and leaf production (and root-weight) was observed in nondiseased plants. In soil infested withP. cinnamomi, plant growth and root weights were much depressed by low soil pH, and especially by low soil pH coupled with high soil moisture contents. These interactions were statistically highly significant. Root weights in pots withP. cinnamomi were closely related to the incidence of disease. A disease index was used to visually assess the conditions of roots. Isolation of the pathogen from diseased plant roots confirmed the accuracy of the disease index. A process of elimination suggsts that favorable soil Ca level and not high pHper se was responsible for disease suppression and that the devastating effects of low soil pH was produced by high Mn (and possibly Al) and associated low levels of Ca and P in soil solutions, which led to breakdown of biological control mechanisms.
    Type of Medium: Electronic Resource
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