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  • 1980-1984  (2)
  • Chemistry  (1)
  • Cytochalasin B and D  (1)
  • Nuclear Reactions
  • Nuclear reactions
  • 1
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 30 (1984), S. 393-401 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Liquid-side mass transfer coefficients were measured for cocurrent two-phase downflow in 5 and 10 cm diameter columns pakced with 2.5 and 4 mm Raschig rings. Experiments were specifically carried out in the pulsing flow regime. The mass transfer coefficients were determined via absorption of CO2 into buffer solutions with the advantage of a high absorbing capacity. Thus columns of 1 m length could be used. Relations are proposed based on the hydrodynamic phenomena observed in pulsing flow. From these relations a correlation for kL is found in terms of flow rates and packing characteristics that satisfies the experimental data.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0878
    Keywords: Cytochalasin B and D ; Endocytosis ; Intestine (human) ; Glycoprotein transport ; Lysosomal degradation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The effect of cytochalasin B (CB) and cytochalasin D (CD) on the endocytotic uptake of horseradish peroxidase (HRP) by intestinal absorptive cells was investigated by morphometric methods. The results showed that CD inhibited endocytosis considerably, and without any detrimental side-effects. CB had hardly any effect on the endocytosis of HRP, but caused a significant decrease in the number of apical vesicles and tubules involved in the transport of cell-coat glycoproteins from the Golgi apparatus to the brush border. Electron-microscopic autoradiographic analysis of the effect of CD showed that although endocytosis is inhibited significantly by the drug, the amount of radiolabelled cell-coat material entering the lysosome-like bodies was unaltered compared with control cultures. These observations support our hypothesis that the cell-coat glycoproteins of the absorptive cells enter the lysosome-like bodies by a crinophagic rather than by an exocytotic-endocytotic mechanism.
    Type of Medium: Electronic Resource
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