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  • 1980-1984  (3)
  • Chemistry  (1)
  • Fabrication process  (1)
  • protein synthesis and degradation  (1)
  • 1
    ISSN: 1573-4927
    Keywords: muscle protein ; protein turnover ; protein synthesis and degradation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Fractional rates (% · day−1) of synthesis and degradation were determined by measuring the output of Nτ-methylhistidine (MeHis) in the excreta at 4 and 8 weeks of age in the chicken. At 4 weeks of age, the fractional rate of synthesis of the meat-type stock was twice that of the egg-type stock (White Leghorn), but the fractional rates of synthesis at 8 weeks of age were similar (4.1–5.1% · day−1) among stocks. The fractional rate of degradation (1.3–1.5% · day−1) of the meat-type stock at 8 weeks of age was less than half the rate of the egg-type stock (2.9% · day−1). The fractional rates of synthesis and degradation at 4 weeks of age in the Satsuma native fowl were relatively high compared with those in the other stocks. In particular, the rate of degradation (8.6% · day−1) at 4 weeks of age was approximately twice that of other stocks. These results show that fractional rates of synthesis and degradation of muscle protein in the chicken differ among genetically diverse groups. The effect of changes in rates of synthesis and degradation on the change in fractional growth rate also differed. From regression coefficients (bK s · FGR and bK d · FGR) of these rates in skeletal muscle protein on the fractional growth rate, it was recognized that the change in growth rate accompanies the changes in both synthesis and degradation in White Leghorn and commercial broilers but only the change in synthesis in White Plymouth Rock (dw) and Satsuma native fowl.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Medical & biological engineering & computing 18 (1980), S. 10-18 
    ISSN: 1741-0444
    Keywords: Biolised cardiac prostheses ; Defect and failure ; Device reliability ; Fabrication process ; Inspection system
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract The clinical application of cardiac prostheses requires a pump that has the highest reliability and no defects. Considering the possibility of clinical implantation in the future, quality control and inspection systems have been incorporated into the fabrication process of biolised cardiac prostheses. Inspection procedures are employed at every strategic point in the pump fabrication process, including visual inspection, dimensional check, material test, performance test and s.e.m. observation. Over the past one-and-a-half years we have inspected 480 components and assemblies from 49 total artificial hearts and left-ventricular assist devices. A total of 93 defects and failures were detected by the inspection system, of which 48 defects were repaired in the fabrication lines. The remaining components were rejected and removed from the pump fabrication lines. The quality of trileaflet dura mater valves was significantly improved by the incorporation of the quality-control system. Since most of the fabrication and assembly are performed manually at the present time, the quality control has contributed greatly to improved device reliability.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 18 (1984), S. 939-951 
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Tensile and fatigue properties were studied on three kinds of segmented polyether polyurethanes developed for blood pump applications. To study the effects of plasma constituents, specimens were immersed in a cholesterol-lipid solution whose composition is similar to that of plasma. The results obtained were compared with those observed in a saline solution which had been reported previously. Immersion in the cholesterol-lipid solution has influence on the mechanical properties of Toyobo TM5 polyurethane and Avcothane 51: Its effect is enhanced by cyclic deformation. Cholesterol-lipids change the mechanical characteristics of Avcothane 51 more remarkably than those of Toyobo TM5 polyurethane possibly because the former contains about 10% silicone. On the other hand, there is little effect of the constituents of the cholesterollipid solution on the static and dynamic mechanical properties of Biomer, although moisture and cyclic deformation have some influence on the mechanical characteristics.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
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