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  • 1
    Electronic Resource
    Electronic Resource
    Dystrophic form of inherited epidermolysis bullosa in a dog (Akita Inu) (1995)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 133 (1995), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We report a dog with dystrophic epidermolysis bullosa. This 4-year-old female Akita Inu, a species of Canis familiaris var. japanicus Temminck, had a 3-year-history of ulcers and scars over the pressure areas on the limbs, and dystrophic nails, since the age of 1 year, which corresponds lo early adulthood in humans. Electron microscopy of a blister revealed separation beneath the lamina densa, and a reduction in the number of anchoring fibrils. The NC-1 domain of type VII collagen was positively stained with monoclonal anlibody LH7.2 at the basement membrane zone. These findings indicate that humans and dogs have a similar response to antibody LH7.2, which may aid the development of an animal model for this disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1995.tb06942.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    d-Glucose transport activities in erythrocytes and hepatocytes of dogs, cats and cattle
    Amsterdam : Elsevier
    Comparative Biochemistry and Physiology -- Part A: Physiology 102 (1992), S. 285-287 
    Details
    ISSN: 0300-9629
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0300-9629(92)90136-E
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Glucose transport and glycolytic enzyme activities in erythrocytes of two-year-old thoroughbreds undergoing training exercise (1994)
    Springer
    Veterinary research communications 18 (1994), S. 417-422 
    Details
    ISSN: 1573-7446
    Keywords: erythrocyte ; enzyme ; exercise ; horse ; glucose transport ; metabolism ; training
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract d-Glucose transport and cytosolic enzyme activities were measured in erythrocytes from 2-year-old thoroughbreds under continuous training exercise (race horses) and compared with those from untrained horses of various ages (sires, mares and untrained 2-year-old thoroughbreds). The activities of the glucose transport and glycolytic enzymes, hexokinase and pyruvate kinase, in the race horses' erythrocytes were elevated to 2–3.5 times above those of untrained horses. There were no significant differences in plasma glucose, triglyceride or IRI concentrations between the horses in training and untrained horses. The increases in glucose transport and glycolytic enzyme activities in their erythrocytes are considered to reflect an increased metabolic activity in the race horses resulting from the training exercises.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01839417
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    A Comparison of the Plasma Fructose Concentrations in Dogs and Cats and Changes in the Fructose Concentrations in Dogs Following Intravenous Administration of Fructose (1999)
    Springer
    Veterinary research communications 23 (1999), S. 203-209 
    Details
    ISSN: 1573-7446
    Keywords: cat ; dog ; free fatty acids ; fructose ; glucose ; plasma ; triglycerides
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The plasma concentrations of fructose, glucose, free fatty acids (FFA) and triglycerides (TG) were measured in dogs and cats. Changes in these concentrations were investigated in dogs by an intravenous fructose tolerance test (IVFTT) at a dose of 0.1 g/kg body weight. Fructose concentrations in the plasma of dogs were significantly higher than those of cats. There was no significant difference in plasma glucose concentrations between dogs and cats. Plasma FFA concentrations decreased and TG concentrations increased after feeding in both dogs and cats. During the IVFTT, the plasma fructose concentrations in the dogs increased rapidly to a peak by 2 min and then decreased to half of the peak by 5 min after the administration of fructose. Administration of fructose resulted in an increase in the plasma TG concentrations and reduced plasma FFA concentrations in the dogs. Only 4% of the administered fructose was detected in the urine of dogs following IVFTT. Plasma fructose was considered to be rapidly absorbed and metabolized in both dogs and cats. However, as with glucose metabolism, there appear to be some differences in fructose metabolism between dogs and cats.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1006203807735
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    A comparison of the activities of certain enzymes related to energy metabolism in leukocytes in dogs and cats (1998)
    Springer
    Veterinary research communications 22 (1998), S. 187-192 
    Details
    ISSN: 1573-7446
    Keywords: cat ; dog ; enzyme ; glucose ; leukocyte ; mitochondria
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The activities of Na〉+,K〉+-ATPase in plasma membrane, of cytosolic enzymes and of glutamate dehydrogenase (GlGD) in mitochondria were measured in leukocytes (WBC) from dogs and cats to clarify the differences in energy metabolism in these cells. Feline WBC had significantly higher activities of hexokinase (HK), pyruvate kinase (PK) and LDH with pyruvate as substrate than did canine WBC. Canine WBC had significantly higher activities of glucokinase (GK) and GlDH than did feline WBC. Feline WBC had unique characteristics of energy metabolism in that the activities of the cytosolic enzymes under anaerobic conditions were significantly higher than those in canine WBC. It therefore appears that there are distinct differences in glucose metabolism in WBC between dogs and cats. WBC enzyme activities are considered to reflect the metabolic state in the whole body of the animal. It is therefore suggested that changes in the activities of certain glycolytic enzymes in WBC may be useful as a diagnostic indicator in some types of metabolic disease in dogs and cats.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1006073305479
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Quality control for fabrication of biolised cardiac prostheses (1980)
    Springer
    Medical & biological engineering & computing 18 (1980), S. 10-18 
    Details
    ISSN: 1741-0444
    Keywords: Biolised cardiac prostheses ; Defect and failure ; Device reliability ; Fabrication process ; Inspection system
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract The clinical application of cardiac prostheses requires a pump that has the highest reliability and no defects. Considering the possibility of clinical implantation in the future, quality control and inspection systems have been incorporated into the fabrication process of biolised cardiac prostheses. Inspection procedures are employed at every strategic point in the pump fabrication process, including visual inspection, dimensional check, material test, performance test and s.e.m. observation. Over the past one-and-a-half years we have inspected 480 components and assemblies from 49 total artificial hearts and left-ventricular assist devices. A total of 93 defects and failures were detected by the inspection system, of which 48 defects were repaired in the fabrication lines. The remaining components were rejected and removed from the pump fabrication lines. The quality of trileaflet dura mater valves was significantly improved by the incorporation of the quality-control system. Since most of the fabrication and assembly are performed manually at the present time, the quality control has contributed greatly to improved device reliability.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02442474
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    Paper (German National Licenses)
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