Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Regulation of pain sensitivity in the central nervous system (1981)
    Oxford, UK : Blackwell Publishing Ltd
    Cephalalgia 1 (1981), S. 0 
    Details
    ISSN: 1468-2982
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Nociceptive information may be inhibited by stimulation of opiate receptors located presynaptically on primary afferent neurons. Sensory signals entering the spinal chord inhibit nociceptive signals by a non-opioid “gate” mechanism. Descending systems also modulate pain sensitivity at the spinal level. The descending 5-hydroxytryptamine (5-HT) system has a tonic inhibitory function, with diurnal fluctuations in intensity. The strong analgesic effects of electrical stimulation and morphine microinjections in certain brainstem structures is probably mediated by other descending systems. The ascending 5-HT system may influence the results of some complex tests for pain sensitivity by altering e.g. emotionality and habituation rate. Acupuncture analgesia involves opioid systems. In high frequency electroacupuncture and transcutaneous nerve stimulation, a non-opioid “gate” mechanism may predominate. Acute stress may produce analgesia by opioid as well as non-opioid mechanisms. The control of pain sensitivity is influenced by learning (e.g. biofeedback techniques and social factors), and may be affected in depression, mania and schizophrenia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1468-2982.1981.tb00008.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Synthesis of new 2-pyridylhydrazones and 2-quinolylhydrazones containing 2-thiophene or 2-furan groups (1983)
    s.l. : American Chemical Society
    Journal of chemical & engineering data 28 (1983), S. 431-432 
    Details
    ISSN: 1520-5134
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/je00034a025
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    facet.materialart.
    Unknown
    Pierre Thillaud. "Les Maladies et la Médecine en Pays Basque Nord: à la fin de l'Ancien Régime (1690-1789)" (Book Review) (1984)
    Oxford : Periodicals Archive Online (PAO)
    Journal of the History of Medicine and Allied Sciences. 39:3 (1984:July) 383 
    Details
    ISSN: 0022-5045
    Topics: History , Medicine
    Notes: Book Reviews
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:6134-1984-039-03-000015
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    The Influence of Matching for SB on MLC Typing Is Significant but Marginal (1984)
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of immunology 19 (1984), S. 0 
    Details
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: To investigate the role of SB in MLC typing responses, reactions of lymphocytes from 23 DW3-positive. HLA-D-heterozygous individuals against 9 Dw3 homozygous typing cells (HTCs) were evaluated. Significantly more clear typing reactions were observed in those combinations that were matched for SB us compared with those that were mismatched. Nevertheless, MLC responses towards HTCs that were HLA-D/DR- and SB-compatible could be very strong. An additional analysis of the influence of HLA-B and the newly defined determinants LB–Q1 and LB–Q2 demonstrated that in combinations that were matched for these markers as well, stabilized relative responses could still he over 100%.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-3083.1984.tb00928.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Methods for biological monitoring: Biological interactions in communities of subtidal sediments (1980)
    Springer
    Helgoland marine research 33 (1980), S. 495-506 
    Details
    ISSN: 1438-3888
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Predation has been demonstrated to be of fundamental importance in structuring benthic communities in the intertidal zone. The aim of the present investigation was to elucidate some of the effects of predation on structuring communities in unvegetated subtidal sediments. Field manipulative cage experiments were performed on sediment in the inner part of the Oslofjord (Norway), where the species composition was typical for a moderately organically enriched sediment. Sediment from this area was transferred to an area not suspected a priori to be seriously affected by organic pollution, and the effect of predation on the fauna was evaluated. Predation effects were not observed in the Oslofjord experiments partially because of extensive obstruction of recruitment to the sediment by settlement ofPolydora antennata on the cage; however, further experiments are in progress in this area. No such settling was observed in the unpolluted area. Here 63 taxonomic groups were identified, 57 in the control and 50 in the cages; 43 taxonomic groups were found in both the cage and the control. The total number of individuals was significantly higher in the cage (4779) than in the control (2849). The fauna recruited to the sediment in the cage responded to decreased predation by macropredators by a significant reduction in diversity. Of the 10 most abundant groups 3 (Tellinacea, Syllidae andPholoë minuta) were significantly more abundant in the cage than in the control; 3 others (Prionospio malmgreni, Microphthalmus abberans and Paraonidea) were significantly more abundant in the control. It is concluded that in an unpolluted area predation is an important factor in controlling numbers of at least some of the most abundant species. However, the effect of predation does not seem to be of the same importance in the subtidal as has previously been recognized for unvegetated intertidal mudflats.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02414774
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Serum-Sialyltransferase activity in cancer patients (1982)
    Springer
    Journal of molecular medicine 60 (1982), S. 445-449 
    Details
    ISSN: 1432-1440
    Keywords: Sialyltransferase ; Malignant diseases ; Sensitivity, specifity ; Tumor marker ; Diagnostic value ; Sialyltransferase ; Maligne Erkrankungen ; Sensitivität, Spezifität ; Tumormarker ; diagnostischer Wert
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die Sialyltransferase-Aktivität wurde bei 116 Patienten mit Tumoren verschiedenen Ursprungs und unterschiedlicher klinischer Stadien im Serum bestimmt. Nur bei Patienten mit Metastasen fand sich eine signifikant erhöhte Serum-Sialyltransferase-Aktivität im Vergleich zum Normalkollektiv. Eine gesteigerte Enzymaktivität wurde aber auch bei Rheumatikern und Hepatitispatienten ermittelt, nicht dagegen bei an zystischer Fibrose erkrankten Kindern. Einige Serien von Tumorpatienten wurden zusätzlich auf andere Tumormarker hin untersucht (Carcinomembryonales Antigen, Alkalische Phosphatase: Regan-Isoenzym, Creatinkinase: BB-Isoenzym, Lactatdehydrogenase: Isoenzym 5), und die Ergebnisse mit den klinischen Diagnosen verglichen. Die Sensitivität und die Spezifität der Serum-Sialyltransferase als Tumormarker wird diskutiert.
    Notes: Summary Serum-sialyltransferase activity was measured in serum samples of 116 patients with malignant tumors of various origins and different clinical stages using asialo-fetuin as the acceptor and cytidine-5′-mono-phospho[14C]sialic acid as the donor. Only patients with metastatic tumors had significantly elevated serum-sialyltransferase levels. Increased enzyme activity was also associated with rheumatoid arthritis and with acute hepatitis, whereas no significant alteration of enzyme activity was observed in cystic fibrosis patients. In a group of tumor patients, various additional tumor markers were determined (carcinoembryonic antigen, alkaline phosphatase: Regan isoenzyme, creatinekinase: BB-isoenzyme, lactatedehydrogenase: isoenzyme 5) and the data compared to the clinical diagnoses. The sensitivity and specifity of serum-sialyltransferase as a tumor marker is assessed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01720358
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Sialyltransferase activity in tumor tissues (1984)
    Springer
    Journal of molecular medicine 62 (1984), S. 331-336 
    Details
    ISSN: 1432-1440
    Keywords: Sialyltransferase ; Tumor tissues ; Tumor markers
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Sialyltransferase (ST) activity was examined in tumor and control tissues. Within each group of control tissues a wide variation in the levels of ST activity was observed. Only in 20% of the tumors was the ST activity above the range of enzyme activity of the corresponding group of control tissues. Compared with its corresponding normal counterpart from the same individual, ST was elevated in tumor tissue by a factor of 2.1 on average. The distribution function indicates an increase in enzyme activity in 74% of the tumors. Other tumor markers were also determined for comparison. The ratio of the lactate dehydrogenase (LDH) subunits (M/H) was increased in tumors by a factor of 1.3 on average; the frequency of increase was 75%. From the distribution function of our data it follows that a decrease in the ratio of the creatine kinase (CK) subunits (B/M) occurs in 56% of tumors, the average factor being 0.8. The Regan isoenzyme of the alkaline phosphatase (AP) could be demonstrated in 13% of the tumors. In serum and in tissues ST was found to be composed of multiple forms. However, an isoenzyme of higher tumor specificity has not yet been established.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01716451
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    facet.materialart.
    Unknown
    Mutations vocaliques dans les dialectes hispano-arabes (1981)
    Leiden : Periodicals Archive Online (PAO)
    Arabica. 28 (1981) 362 
    Details
    ISSN: 0570-5398
    Topics: Linguistics and Literary Studies , Ethnic Sciences , History , Theology and Religious Studies
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:r567-1981-028-00-000004
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    facet.materialart.
    Unknown
    M. RODINSON, "La fascination de l'Islam" (Book Review) (1983)
    Leiden : Periodicals Archive Online (PAO)
    Arabica. 30 (1983) 92 
    Details
    ISSN: 0570-5398
    Topics: Linguistics and Literary Studies , Ethnic Sciences , History , Theology and Religious Studies
    Notes: Bulletin critique
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:r567-1983-030-00-000058
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 10
    Electronic Resource
    Electronic Resource
    Metergoline elevates or reduces nociceptive thresholds in mice depending on test method and route of administration (1984)
    Springer
    Psychopharmacology 82 (1984), S. 306-309 
    Details
    ISSN: 1432-2072
    Keywords: 5-Hydroxytryptamine ; Metergoline ; Tailflick test ; Hot-plate test ; Nociception ; Mouse
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Intrathecal injection of metergoline reduced the response latencies in the tail-flick and hot-plate tests, supporting the contention that descending 5-hydroxytryptamine (5-HT) pathways tonically inhibit pain sensitivity. Elevated latencies were, however, observed after both intraperitoneal (IP) and intracerebroventricular (ICV) injections in the hot-plate test, when hindpaw lick was used as the response criterion. These findings may indicate that supraspinal 5-HT pathways tonically increase pain responsiveness in certain test situations. Alternative hypotheses are that metergoline in supraspinal structures acts as an agonist at post-synaptic 5-HT receptors mediating antinociception, or as an antagonist at pre-synaptic 5-HT receptors. Recording of first reaction latencies on the hot-plate showed increased thresholds after IP, but not after ICV injections. This may indicate an action on 5-HT receptors in the brain not accessible after ICV injections, or that the effect is mediated by blockade of peripheral 5-HT receptors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00427675
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...