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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Calcified tissue international 35 (1983), S. 591-595 
    ISSN: 1432-0827
    Keywords: Parathyroid hormone ; Bone marrow blood ; Antecubital vein blood ; Arterio-venous differences
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary Parathyroid hormone (PTH) concentrations were compared in blood drawn from the bone marrow and antecubital vein of patients undergoing marrow biopsy for suspected hematological neoplasia. Radioimmunological analysis revealed that the bone marrow blood had a higher PTH content than blood from the peripheral circulation. Thyroid hormone-binding globulin was not distributed asymmetrically, showing that the gradient is PTH specific. The intact PTH content of marrow blood was 65% greater than that in the venous system, whereas carboxyl regional PTH levels showed a 34% gradient in favor of the marrow. Although the majority of patients were found to have hematological malignancies, there was no discernable influence of tumor on the PTH gradients. The physiological implications and possible origins of the asymmetrical PTH distribution are discussed.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1440
    Keywords: Bone-marrow blood ; Parathyroid hormone ; Osteoporosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Recently the bone-marrow cavity blood concentration of parathyroid hormone (PTH) has been shown to exceed that of the peripheral blood. As PTH is a primary modulator of bone cell activity, altered levels of the hormone in the bone-marrow blood may play a significant role in the aetiology of bone disease. We therefore measured PTH concentrations in marrow cavity and venous blood of 9 osteoporotic and 14 control subjects using sequence specific radioimmunoassays for intact and mid-carboxyl (Mid-C) regional human PTH (hPTH). Intact and Mid-C PTH levels were identical in the peripheral blood of control and osteoporotic subjects. Furthermore, bone-marrow cavity blood concentrations of Mid-C PTH, whilst universally higher than those found in peripheral blood, were also comparable in the osteoporotic and control subjects. The sole difference in the PTH composition of bone-marrow cavity blood from osteoporotic subjects was an increased concentration of intact PTH. The origins and consequences of elevated levels of intact PTH within the marrow cavity blood of osteoporotic subjects are discussed.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of consumer policy 5 (1981), S. 366-366 
    ISSN: 1573-0700
    Source: Springer Online Journal Archives 1860-2000
    Topics: Economics
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of consumer policy 5 (1981), S. 39-50 
    ISSN: 1573-0700
    Source: Springer Online Journal Archives 1860-2000
    Topics: Economics
    Description / Table of Contents: Abstract As indicated by the title the authors are convinced that obsolescence is no special marketing strategy. Therefore the phenomenon should not be regarded as a subject worthy of study by itself. The authors reject the hypothesis that product quality is eroded by increasing monopolization, a position taken by bourgeois as well as marxian critics. In market economies there will always be production of “good” and “bad” consumer goods depending on productive capacity and sellers' competition for effective demand. The well-known social problems (pollution, shortage of raw materials, etc.) are not caused by decreasing product quality but are due to the need for reproduction of capital on a larger scale. The “enormous production of goods” cannot be separated by scientific methods into (a) an economic normality (technical progress) and (b) a perverse exaggeration not acceptable on moral grounds (obsolescence). Neither do the strategies of obsolescence indicate the decadence of monopolistic capitalism. Instead the abundance of consumer goods should be interpreted as a dialectic result of a society's profit maximization. To give an example: After well-equipped television sets with a high technical standard had been developed, the system starts supplying units of a hypertrophic size and capacity.
    Notes: Zusammenfassung Wie im Titel angedeutet, gehen die Verfasser davon aus, daß sich hinter dem Obsoleszenz-Phänomen keine besondere Absatzstrategie der Unternehmen und daher kein eigenständiges Erkenntnisobjekt verbirgt. Die von bürgerlichen und marxistischen Kritikern vielfach geäßerte Ansicht, mit zunehmender Vermachtung/Monopolisierung der Märkte seien die Waren schlechter geworden, wird nicht geteilt. Nach wie vor werden bei uns sehr viele «gute» sowie «schlechte» Konsumgüter hergestellt, je nach dem wie die Produktivkräfte sowie die Konkurrenz um die zahlungskräftige Nachfrage es erlauben. Was die bekannten gesamtgesellschaftlichen Probleme (Umweltbelastung, Rohstoffknappheit etc.) verursacht und die Wissenschaften auf dem Plan gerufen hat, ist nicht die abnehmende Qualität der Waren, sondern die erweiterte Reproduktion kapitalistischen Wirtschaftens schlechthin. Die «ungeheure Warenansammlung» kann wissenschaftlich nicht zerlegt werden in eine unanfechtbare Normalität (=technischer Fortschritt) und moralisch abzulehnende Auswüchse (=Obsoleszenz); ebensowenig signalisieren Obsoleszenzstrategien die allgemeine Dekadenz des Monopolkapitals. Der Reichtum an Konsumgütern ist vielmehr zu begreifen als dialektisches Resultat einer Erwerbsgesellschaft, die-beispielhaft konkretisiert-überdimensionierte Fernsehgeräte zum Kauf anbietet, nachdem sie zuvor technisch ausgereifte Geräte entwickelt hat.
    Type of Medium: Electronic Resource
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