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  • 1980-1984  (6)
  • 1
    Electronic Resource
    Electronic Resource
    Structure of Mitochondrial Dna From Paramecium Tetraurelia (1980)
    Oxford, UK : Blackwell Publishing Ltd
    The @journal of eukaryotic microbiology 27 (1980), S. 0 
    Details
    ISSN: 1550-7408
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Mitochondrial DNA (mtDNA) from endosymbiote-free stocks of Paramecium tetraurelia was isolated by 2 procedures. the buoyant density of the mtDNA in neutral CsCI was 1.702 gm/cm3. a value consistent with the melting temperature of the mtDNA. Only linear molecules were observed by electron microscopy. These molecules were homogeneous in size with a monomer molecular weight of 25.6 × 106 daltons. the size of the mtDNA determined after digestion with the restriction endonucleases EcoRI or Hind III agreed with the value obtained by electron microscopy. These studies also revealed that the digestion pattern of mtDNA from stock 172 differed from that of the other 3 stocks (51, 127. 203) examined. Some mtDNA molecules exhibited snapback reassociation following denaturation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1550-7408.1980.tb04687.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Molecular genetics: Ciliates come of age (1984)
    [s.l.] : Nature Publishing Group
    Nature 310 (1984), S. 453-454 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] FROM what organism was a catalytic RNA molecule first isolated and characterized? Where can one find an animal that, at one time in its life cycle, has giant polytene chromosomes like those ofDrosophila but at another time has each gene on a separate small molecule? In what organism does ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/310453a0
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Teaching mechanisms (1983)
    [s.l.] : Nature Publishing Group
    Nature 302 (1983), S. 637-637 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE nineteenth-century promise that the study of cells, their components and their products would illuminate all aspects of biology has been amply fulfilled in recent years, so much so that writing a comprehensive treatise on cell biology is a formidable task, some would say impossible. It is ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/302637a0
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Extra genes, in and out of chromosomes (1982)
    [s.l.] : Nature Publishing Group
    Nature 298 (1982), S. 875-875 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] WHEN mammalian tissue cultures are treated with gradually increasing concentrations of methotrexate (MTX), cell lines can be selected that are resistant to very high concentrations of the otherwise toxic drug. The basis of resistance may be decreased permeability of the cells to the drug or ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/298875a0
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  • 5
    Electronic Resource
    Electronic Resource
    In vitro RNA synthesis in oocyte nuclei of the newt Notophthalmus (1981)
    Springer
    Chromosoma 82 (1981), S. 171-187 
    Details
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract An incubation medium is described which supports RNA synthesis in isolated oocyte nuclei of the newt Notophthalmus, and which permits subsequent autoradiographic examination of the lampbrush chromosomes and nucleoli. By using different concentrations of α-amanitin we distinguish RNA synthesis due to RNA polymerases I, II and III. All RNA synthesis on loops is inhibited by 0.5 μ/ml of α-amanitin and is therefore due to polymerase II. Polymerase III is responsible for RNA synthesis at a small number of discrete sites in condensed chromatm. These include the centromere bars of three of four chromosomes, which probably represent 5S RNA synthesis, as well as 15–20 lesser sites scattered elsewhere. Polymerase I activity is confined to the nucleoli.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00286102
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  • 6
    Electronic Resource
    Electronic Resource
    Histone genes are located at the sphere loci of newt lampbrush chromosomes (1981)
    Springer
    Chromosoma 84 (1981), S. 159-171 
    Details
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract In situ hybridization experiments on mitotic and lampbrush chromosomes show that histone genes and an associated 222 bp repeated sequence, satellite 1, are located at or near the sphere loci of chromosomes 2 and 6 of the newt Notophthalmus viridescens. During the lampbrush chromosome stage, transcripts of the histone genes and of satellite 1 occur on loops associated with the spheres. Histone genes are located at sites on the mitotic chromosomes of Triturus cristatus and T. alpestris which are consistent with the known positions of spheres on their lampbrush chromosomes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00399128
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