Bibliothek

X
feed icon rss

Ihre E-Mail wurde erfolgreich gesendet. Bitte prüfen Sie Ihren Maileingang.

Leider ist ein Fehler beim E-Mail-Versand aufgetreten. Bitte versuchen Sie es erneut.

Vorgang fortführen?

Exportieren
  • 1
    Digitale Medien
    Digitale Medien
    Alteration of the Tetrahymena Genome During Nuclear Differentiation*† (1979)
    Oxford, UK : Blackwell Publishing Ltd
    The @journal of eukaryotic microbiology 26 (1979), S. 0 
    Details
    ISSN: 1550-7408
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie
    Notizen: Synopsis.The DNA of the macro- and the micronucleus of Tetrahymena thermophila has been compared by various biochemical methods. It became evident from their thermal denaturation temperatures and buoyant densities that the 2 DNAs were very similar in overall composition. Small differences were detected when the sequence complexities of these DNAs were compared by DNA renaturation studies. The studies suggested that ˜ 10% of the micronuclear genome was lost or underrepresented in the macronucleus. Comparison of individual gene levels revealed further differences. By using the technic of gene cloning a micronuclear sequence was isolated which hybridized only with micronuclear, but not with macronuclear DNA. These results indicated the occurrence of elimination or underreplication of this sequence in the macronucleus. Gene amplification was also shown to occur. In the micronucleus only a single copy of rDNA was found integrated into the chromosome. During macro-nuclear development, amplification was observed to occur, and the amount of rDNA to increase, until there were ˜ 200 copies per haploid genome in the mature macronucleus. all of them extrachromosomal and palindromic. The 3rd case of alteration involved a simple repeated sequence, (CCCCAA)n, present in the termini of rDNA and also in many other locations of the genome. Restriction endonuclease digestion studies revealed drastic differences in the organization of the repeats between macro-and micronucleus. These differences may be interpreted as the results of chromosome fragmentation which occurs at every cluster of the repeats during macronuclear development. The relationship between this event and gene amplification and elimination is discussed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1550-7408.1979.tb02723.x
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 2
    Digitale Medien
    Digitale Medien
    Structure of Mitochondrial Dna From Paramecium Tetraurelia (1980)
    Oxford, UK : Blackwell Publishing Ltd
    The @journal of eukaryotic microbiology 27 (1980), S. 0 
    Details
    ISSN: 1550-7408
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie
    Notizen: Mitochondrial DNA (mtDNA) from endosymbiote-free stocks of Paramecium tetraurelia was isolated by 2 procedures. the buoyant density of the mtDNA in neutral CsCI was 1.702 gm/cm3. a value consistent with the melting temperature of the mtDNA. Only linear molecules were observed by electron microscopy. These molecules were homogeneous in size with a monomer molecular weight of 25.6 × 106 daltons. the size of the mtDNA determined after digestion with the restriction endonucleases EcoRI or Hind III agreed with the value obtained by electron microscopy. These studies also revealed that the digestion pattern of mtDNA from stock 172 differed from that of the other 3 stocks (51, 127. 203) examined. Some mtDNA molecules exhibited snapback reassociation following denaturation.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1550-7408.1980.tb04687.x
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 3
    Digitale Medien
    Digitale Medien
    CAJAL BODIES: The First 100 Years (2000)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Cell and Developmental Biology 16 (2000), S. 273-300 
    Details
    ISSN: 1081-0706
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Biologie , Medizin
    Notizen: Abstract Cajal bodies are small nuclear organelles first described nearly 100 years ago by Ramon y Cajal in vertebrate neural tissues. They have since been found in a variety of animal and plant nuclei, suggesting that they are involved in basic cellular processes. Cajal bodies contain a marker protein of unknown function, p80-coilin, and many components involved in transcription and processing of nuclear RNAs. Among these are the three eukaryotic RNA polymerases and factors required for transcribing and processing their respective nuclear transcripts: mRNA, rRNA, and pol III transcripts. A model is discussed in which Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA. A parallel is drawn to the nucleolus and the preassembly of ribosomes, which are unitary particles involved in translation of proteins.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1146/annurev.cellbio.16.1.273
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 4
    Digitale Medien
    Digitale Medien
    Through the looking glass (2006)
    [s.l.] : Nature Publishing Group
    Nature medicine 12 (2006), S. 1142-1145 
    Details
    ISSN: 1546-170X
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Medizin
    Notizen: [Auszug] After much urging, my parents bought me a microscope when I was 14 years old, not one of the toys I had struggled with up to that time, but the real thing, with crystal-sharp images and an oil immersion objective (Fig. 1). Once I was hooked on the vast world that lay beyond what I could see with my ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nm1006-1142
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 5
    Digitale Medien
    Digitale Medien
    Kinetics of Deoxyribonuclease Action on Chromosomes (1963)
    [s.l.] : Nature Publishing Group
    Nature 198 (1963), S. 36-38 
    Details
    ISSN: 1476-4687
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik
    Notizen: [Auszug] THE fine structure of chromosomes remains an enigma JL despite detailed knowledge about their component molecules. There is general agreement, based primarily on evidence from electron microscopy., that chromosomes contain delicate fibres of about 100 A diameter1, and the assumption is widely made ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/198036a0
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 6
    Digitale Medien
    Digitale Medien
    Evolving editions (1988)
    [s.l.] : Nature Publishing Group
    Nature 332 (1988), S. 27-28 
    Details
    ISSN: 1476-4687
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik
    Notizen: [Auszug] JIM Watson's Molecular Biology of the Gene was first published in 1965. The book brought together for the first time the new prokaryotic genetics and the new biochemistry of nucleic acids and pro-teins, and it was enormously popular. The success of the first edition was a tribute to Watson's ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/332027c0
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 7
    Digitale Medien
    Digitale Medien
    Tying up the loose ends (1990)
    [s.l.] : Nature Publishing Group
    Nature 344 (1990), S. 108-109 
    Details
    ISSN: 1476-4687
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/344108a0
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 8
    Digitale Medien
    Digitale Medien
    Molecular genetics: Ciliates come of age (1984)
    [s.l.] : Nature Publishing Group
    Nature 310 (1984), S. 453-454 
    Details
    ISSN: 1476-4687
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik
    Notizen: [Auszug] FROM what organism was a catalytic RNA molecule first isolated and characterized? Where can one find an animal that, at one time in its life cycle, has giant polytene chromosomes like those ofDrosophila but at another time has each gene on a separate small molecule? In what organism does ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/310453a0
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 9
    Digitale Medien
    Digitale Medien
    What's going on in the cell? (1986)
    [s.l.] : Nature Publishing Group
    Nature 323 (1986), S. 401-401 
    Details
    ISSN: 1476-4687
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik
    Notizen: [Auszug] ALTHOUGH many of the principles of cell biology were well established a generation or more ago, the sheer volume of molecular data gathered in recent years has transformed the subject. As usual in a rapidly advancing science, the explosion of information has resulted from an interplay between new ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/323401a0
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 10
    Digitale Medien
    Digitale Medien
    Teaching mechanisms (1983)
    [s.l.] : Nature Publishing Group
    Nature 302 (1983), S. 637-637 
    Details
    ISSN: 1476-4687
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik
    Notizen: [Auszug] THE nineteenth-century promise that the study of cells, their components and their products would illuminate all aspects of biology has been amply fulfilled in recent years, so much so that writing a comprehensive treatise on cell biology is a formidable task, some would say impossible. It is ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/302637a0
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
Schließen ⊗
Diese Webseite nutzt Cookies und das Analyse-Tool Matomo. Weitere Informationen finden Sie hier...