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Multiorgan aluminium deposits in a chronic haemodialysis patient (1984)

Roth, A. ; Nogues, C. ; Galle, P. ; [et al.]

Springer

Virchows Archiv 405 (1984), S. 131-140

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ISSN: 1432-2307

Keywords: Aluminium-intoxication ; Haemodialysis ; Encephalopathy ; Cardiomyopathy ; Lysosomes

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary The study reports an aluminium-intoxicated haemodialysis patient who had encephalopathy, osteomalacia and congestive cardiomyopathy prior to his death. Detailed light and electron microscope examination revealed the presence of aluminium deposits within lysosomes of cells from many organs, including the kidney, liver, brain and heart. The heavy aluminium deposits in myocardial lysosomes favor a possible role of the trace element in the patient's congestive cardiomyopathy.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00694931

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