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  • 1975-1979  (1)
  • 1970-1974  (1)
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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 5 (1978), S. 0 
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. Prazosin had a marked inhibitory effect on post-synaptic a-receptors in the pithed rat, as measured by the blood pressure response to the cumulative administration of clonidine.2. Prazosin had no inhibitory effect, however, on the pre-synaptic a-receptor, as measured by the clonidine-induced reduction in the tachycardia produced by stimulation of the cardiac nerves.3. These results suggest that prazosin has a selective antagonistic affinity for post-synaptic a-receptors.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 1 (1974), S. 0 
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: SUMMARY 1. The effects of caffeine, halothane, potassium chloride and procaine have been studied on normal human skeletal muscle in vitro. Particular emphasis has been given to the role played by extracellular calcium ions in producing these effects.2. Caffeine produces a concentration-dependent contracture probably by stimulating the release of calcium ions from the calcium storing membranes of the muscle cell.3. Halothane potentiates the contractures produced by caffeine and potassium chloride probably by facilitating the release of calcium from the storage membranes.4. Potassium chloride produces a contracture only in the presence of caffeine or halothane.5. Procaine inhibits all the contractures studied.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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