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  • 1975-1979  (1)
  • 1965-1969  (2)
  • 1935-1939  (1)
  • 1920-1924
  • Life and Medical Sciences  (3)
  • Micropuncture  (1)
Material
Years
  • 1975-1979  (1)
  • 1965-1969  (2)
  • 1935-1939  (1)
  • 1920-1924
  • 1990-1994  (1)
Year
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 306 (1979), S. 287-293 
    ISSN: 1432-1912
    Keywords: 2.4-diamino-6.7-dialkylpteridine ; Diuretics ; Micropuncture ; Tubular transport ; Rat kidney
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The excretion of the diuretic substance DADMP (2.4-diamino-6.7-dimethylpteridine) and of DMP (6.7-dimethylpterin) was studied on single nephrons of the rat kidney using microperfusion and microinjection techniques. In the proximal tubule only DADMP was reabsorbed to a significant degree. Fractional reabsorption rate was independent of the load applied and the permeability constant was found to be 2.2·10−4 cm·s−1. Similar results were obtained in nephrons in which the substances, with inulin, were injected from middle proximal tubular puncture sites and recovered in the urine. DMP appeared in the urine quantitatively and simultaneously with the injected inulin. DADMP recovery, however, was only 20–30% of the injected load during the injection period and after 2 h some 70% was recovered from the urine of both kidneys. The reabsorbed fractions were independent of the loads applied, which varied between 2·10−13 mol·min−1 and 10−9 mol·min−1. A comparison of the microperfusion and the microinfusion data suggests that the reabsorption of DADMP occurs predominantly in the proximal convolution, and it appears that the differences between the renal handling of DMP and DADMP are explicable by their different lipid solubilities.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal of Morphology 124 (1968), S. 79-82 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: A total of 1125 normal chick embryos, representing 25 each of the 45 stages of Hamburger and Hamilton, were removed, fixed in Bouin's solution, stored in 70% ethanol and weighed with a semi-micro analytical balance. Entire blastoderms of stages 1-8 were weighed, whereas only embryos-proper were weighed in stages 9-45. As a consequence, results constituted two groups, each of which showed a geometric rate of growth marked only by minor deviations which were related to specific events of normal growth and development.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 161 (1968), S. 247-252 
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Microcurie amounts of p32, Na22, Fe59, and Cl36 in normally occurring compounds were injected directly into the vitelline vessels of developing chick embryos at stage 24 (Hamburger and Hamilton, '51). The surviving embryos were sacrificed at stage 41. Hearts were removed and examined intact or sectioned for later examination. Coronary vessels were identified, classified according to size (large, diameter = 〉 80 μ; medium, diameter = 40-80 μ; small, diameter 〈 40 μ) and counted. There was a significant increase in the numbers of small and medium vessels which had developed in the presence of gamma radiation emitted by Na22- and Fe59-compounds. The p32- and Cl36-containing compounds did not affect the numbers of vessels of any size. The resulting increased vascularity is shown to be a matter of a distinct increase in numbers of blood vessels as opposed to a simple alteration of the normally occurring vessels.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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