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  • 1
    ISSN: 1432-1440
    Keywords: Deep vein thrombosis ; phlebography ; postoperative ; fibrinogen test ; postthrombotic syndrom ; Tiefe Venenthrombose ; Phlebographie ; postoperativ ; Fibrinogentest ; postthrombotisches Syndrom
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Im Rahmen einer prospektiven, randomisierten und kontrollierten Studie, in der die Thromboseprophylaxe-Mittel Dextran und Heparin bei allgemein-chirurgischen und urologischen Patienten geprüft werden, phlebographierten wir 31 Patienten mit sicherer tiefer Venenthrombose sofort nach der Diagnosestellung mittels125J-Fibrinogentest. 16 Patienten wurden 14 Tage später ein zweites Mal phlebographiert.Alle Thromben entstanden intraoperativ. 24 von 31 Patienten zeigten einemultifokale Entstehung der Thromben. Unabhängig vom Prophylaxe-Mittel und der eingeleiteten Therapie machten die Thromben in den ersten 14 Tagen nach deren Entstehung folgende Veränderungen durch: 9 retrahierten sich, 6 verschwanden, ohne Wandveränderungen aufzuweisen, und 1 verschloß das befallene Gefäß noch vollständig. 2 Thromben verschwanden ohne jegliche Therapie; 4 weitere unter Heparin- und/oder Phenprocoumonbehandlung.
    Notes: Summary Phlebography was carried out in a prospective randomised, controlled study during which dextran and small doses of s.c. heparin have been compared in general surgical and urological patients, in 31 persons with proven deep vein thrombosis diagnosed with the125I-fibrinogen test. In 16 out of the 31 patients a second phlebogram could be performed two weeks later. In this study all thrombi occurred intraoperatively. In 24 of the 31 patients, the appearance of thrombi was multilocular. Independent of the prevention instituted and irrespective of the therapy, the following phenomena could be seen 14 days after the first phlebogram: 9 thrombi retracted, 6 disappeared completely and 1 occluded the vein completely. 2 thrombi disappeared without any therapy whatsoever, the 4 others disappeared in patients receiving heparin and/or coumarin for treatment.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 12 (1977), S. 319-322 
    ISSN: 1432-1041
    Keywords: Clonidine ; Yohimbine ; sleep ; REM sleep
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Clonidine (300 µg orally) increased in man the total duration of sleep and strikingly reduced the duration of REM sleep. Yohimbine (10 mg per os) did not alter the sleep patterns in man but antagonized the effects of clonidine. These results provide evidence that an α sympathomimetic mechanism could suppress REM sleep and increased the total duration of sleep.
    Type of Medium: Electronic Resource
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