ISSN:
1432-1246
Keywords:
Amylphenol
;
Biological monitoring
;
Butylcatechol
;
Butylphenol
;
Isopropylcatechol
;
Methylcatechol
;
Nonylphenol
;
Octylphenol
;
Phenylphenol
;
Urinalysis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary GLC systems are developed for quantitative urinalysis of leucodermogenic phenols and catechols, i. e., p-tert.-butylphenol, p-tert. Amyphenol, p-octylphenol, p- and o-phenylphenol, 3- and 4-methylcatechol, 3-isopropylcatechol, and 4-tert.-butylcatechol. The systems were successfully applied for the exposure assessment of the workers in factories producing p-tert.-butylphenol, p-octylphenol and/or 4-tert.-butylcatechol. In accordance with estimated exposure intensities, the concentrations in the urine of product packers were higher than those of plant operators and engineers. The levels were reduced by the improvement of hygienic conditions in the workshops. Importance of biological monitoring is discussed in relation with the possible skin penetration. From the data obtained, BP concentration in urine, 2 μg/ml, is tentatively proposed as a urinary biological threshold limit value to prevent leucodermogenic effect.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00381797
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