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  • 1975-1979  (3)
  • Chemistry  (3)
  • General Chemistry
  • Sila-perfumes
  • 1
    Electronic Resource
    Electronic Resource
    Sila-Pharmaka, 11. Diphenyl(3-piperidinopropyl)silanol, ein Sila-Analogon des Difenidols (1979)
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 1979 (1979), S. 1554-1559 
    Details
    ISSN: 0170-2041
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Sila-Drugs, 11.  -  Diphenyl(3-piperidinopropyl)silanol, a Sila-Analogue of DifenidolDiphenyl(3-piperidinopropyl)silanol (6b), a sila-analogue of the drug difenidol (6a), and its methoiodide 7 were synthesized for the first time according to scheme 1.  -  The pharmacological and toxicological properties of the analogues 6a and 6b were investigated comparatively.
    Notes: Diphenyl(3-piperidinopropyl)silanol (6b), ein Sila-Analogon des Arzneimittels Difenidol (6a), und dessen Methoiodid 7 wurden erstmals gemäß Schema 1 synthetisiert.  -  Die pharmakologischen und toxikologischen Eigenschaften der Analoga 6a und 6b wurden vergleichend untersucht.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jlac.197919791014
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  • 2
    Electronic Resource
    Electronic Resource
    Sila-Pharmaka, 181) Derivate des 1-(4-Chlorphenyl)silacyclohexans mit 3-(Diethylamino)propyl- und 2-(Diethylamino)ethyl-Gruppierungen (1979)
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 1979 (1979), S. 1915-1924 
    Details
    ISSN: 0170-2041
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Sila-Drugs, 181). - Derivatives of 1-(4-Chlorophenyl)silacyclohexane with 3-(Diethylamino)propyl and 2-(Diethylamino)ethyl GroupsThe preparation of the compounds 3a (and 3b) and 10, which derive from 1-(4-chlorophenyl)-1-(2-diethylaminoethoxy)silacyclohexane (sila-chlorophencyclane, IIa), is described. Compound 3b has been investigated pharmacologically and toxicologically. The biological properties of 3b and those of IIa (and chlorophencyclane) and its hydrochloride IIb are compared.
    Notes: Die Darstellung der Verbindungen 3a (sowie 3b) und 10, die sich vom 1-(4-Chlorphenyl)-1-(2-diethylaminoethoxy)silacyclohexan (Sila-Chlorphencyclan, IIa) ableiten, wird beschrieben. Die Verbindung 3b wurden pharmakologisch und toxikologisch untersucht. Die biologischen Eigenschaften von 3b wurden mit denen von IIa (sowie Chlorphencyclan) und seinem Hydrochlorid IIb verglichen.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jlac.197919791128
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  • 3
    Electronic Resource
    Electronic Resource
    Neue anorganische Ringsysteme. 34. Derivate eines Cyclo-1-thiaIV- und eines Cyclo-1-thiaIV- 3,4-disila-2,5-diazans (1978)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 445 (1978), S. 102-106 
    Details
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Novel Inorganic Ring Systems. 34. Derivatives of the Cyclo-1-thiaIV- and of the Cyclo-1-thia VI-3,4-disila-2,5-diazaneVariations of fivemembered “hetero” cyclosilazanes of the type Si2N2El could be enlarged to the systems with El = SO and SO2. They are obtained by the formation principles 4 + 1 and 2 + 3 respectively, according to the equation (1), (4) and (5). The prepared compound are described in their properties and confirmed in their structure (Tables 1-2).
    Notes: Die Variationen Fünfgliedriger „Hetero“ Cyclosilazane des Typs Si2N2El konnten auf die Systeme mit El = SO und SO2 ausgedehnt werden. Diese entstehen nach den Bauprinzipien 4 + 1 bzw. 2 + 3 gemäß den Reaktionen (1), (4) und (5). Die dargestellten Verbindungen werden in ihren Eigenschaften beschrieben und in ihrer Struktur (vgl. Tab. 1-2) sichergestellt.
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19784450113
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    Paper (German National Licenses)
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