Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Early molecular events in the interaction of enveloped viruses with cells (1979)
    Springer
    European biophysics journal 5 (1979), S. 11-23 
    Details
    ISSN: 1432-1017
    Keywords: Fluorescence polarization degree ; Fusion ; Label migration ; Lipid migration ; Cell membrane ; Virus envelope
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Abstract The fluorescence depolarization of 1,6-diphenyl-hexatriene was used to study the dynamic properties of the hydrophobic regions of the lipid envelopes of ortho- and paramyxoviruses as well as of the Rous sarcoma virus and of the membrane lipids of susceptible and nonsusceptible cells. The systems investigated where active and inactive influenza viruses, and NDV virus acting on chick embryo fibroblasts and Rous sarcoma virus acting on susceptible (C/E) and nonsusceptible (C/B) chicken-cell. Polarization degrees and mean rotational correlation times of DPH embedded in viral lipids were significantly higher than those of DPH in the cell membranes, due to a higher rigidity of the virus envelopes. When suspensions of labelled viruses and unlabelled cells or unlabelled viruses and labelled cells were mixed, a characteristic change of the fluorescence polarization degrees with time was observed. This behaviour was ascribed to a label transfer from virus to cell membranes or vice versa. While the rate constants of label transfer from virus to cells and cells to virus were about the same for the penetrating viruses the rate constants of label release from inactive virus to cells were much larger than for the migration in the opposite direction.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00535769
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Synthese des N-[2-Hydroxy-2-(5-pyrimidinyl)äthyl]phthalimids (1975)
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 1975 (1975), S. 1252-1256 
    Details
    ISSN: 0075-4617
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Synthesis of N-[2-Hydroxy-2-(5-pyrimidinyl)ethyl]phthalimideStarting from 5-(diazoacetyl)pyrimidine (7) the synthesis of N-[2-Hydroxy-2-(5-pyrimidinyl)ethyl]phthalimide via the intermediates 8→ is described. Attempts to reduce the diazoketone 7 to the aminoalkanol 5 failed.
    Notes: Ausgehend von 5-(Diazoacetyl)pyrimidin (7) wird die Synthese von N-[2-Hydroxy-2-(5-pyrimidinyl)äthyl]phthalimid (10) über die Zwischenstufen 8→9 beschrieben. Die direkte reduktive Umwandlung von 7 zum aminoalkohol 5 gelingt nicht.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jlac.197519750704
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Intramolekulare Aromatenalkylierungen, IV. Synthese und Reduktion von N-Methyl-5,6,7,8-tetrahydrochinaldiniumjodid (1976)
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 1976 (1976), S. 610-616 
    Details
    ISSN: 0075-4617
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Intramolecular Alkylations of Aromatic Compounds, IV.  -  Synthesis and Reduction of N-Methyl-5,6,7,8-tetrahydroquinaldinium iodideThe synthesis of N-methyl-5,6,7,8-tetrahydroquinaldinium iodide (11) from 3-butyn-2-one (5) and 3-amino-2-cyclohexen-1-one (6) via the intermediate 6-methyl-5-aza-1-tetralone (9) is described. Reduction of the title compound11 by sodium borohydride gives the octahydro-and decahydroquinaldine derivatives 12a and 14a. Attempted partial catalytic hydrogenation of 11 does not lead to 12a but to 14a.
    Notes: Es wird die Synthese von N-Methyl-5,6,7,8-tetrahydrochinaldiniumjodid (11) aus 3-Butin-2-on (5) und 3-Amino-2-cyclohexen-1-on (6) über die Zwischenstufe 6-Methyl-5-aza-1-tetralon (9) beschrieben. Die Reduktion der im Titel genannten Verbindung 11 mit Natriumborhydrid liefert die Octahydro- und Decahydrochinaldin-Derivate 12a und 14a. Eine partielle Hydrierung von 11 zu 12a auf katalytischem Wege gelingt nicht; es entsteht vielmehr die perhydrierte Verbindung 14a.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jlac.197619760404
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Synthese von cis-3, 10b-Dimethyl-1,2,3,4,4a,5,6,10b-octahydrobenzo[f]isochinolin (1978)
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 1978 (1978), S. 1963-1967 
    Details
    ISSN: 0075-4617
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Intramolecular Alkylations of Aromatic Compounds, VI.  -  Synthesis of cis-3,10b-Dimethyl-1,2,3,4,4a,5,6,10b-octahydrobenzo[f]isoquinolineThe title compound 4 is stereoselectively formed by intramolecular cyclisation of the tetrahydropyridine derivative 3. which in turn can be prepared via steps 5→10. Reduction of the nitrile 5 with Raney nickel in formic acid immediately yields the aldehyde 6.
    Notes: Die im Titel genannte Verbindung 4 ist stereoselektiv durch intramolekulare Cyclisierung des Tetrahydropyridins 3 darstellbar, das seinerseits über die Stufenfolge 5→10 aufgebaut wird. Der Aldehyd 6 ist durch Reduktion des Nitrils 5 mit Raney-Nickel in Ameisensäure direkt zugänglich.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jlac.197819781210
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Intramolekulare Aromatenalkylierungen, V1) Synthese und Umsetzung von 5,6,7,8-Tetrahydro-8-chinolon (1976)
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 1976 (1976), S. 1351-1356 
    Details
    ISSN: 0075-4617
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Intramolecular Alkylations of Aromatic Compounds, V 1). - Synthesis and Reaction of 5,6,7,8-Tetrahydro-8-quinolone5,6,7,8-Tetrahydro-S-quinolone (5) is prepared by catalytic hydrogenation of the ozonide 4. The 2-pyridyl ketones Sa-Sd, which have analogous structures to 5, as well as the tetra- hydroquinolone 10 react with phenyllithium in ether to give the expected benzyl alcohols 9a-9d and 11, whereas the corresponding reaction with 5 to give 12 is only successful when 1,2-dimethoxyethane is added as solvent to the reaction mixture.
    Notes: 5,6,7,8-Tetrahydro-S-chinolon (5) ist durch katalytische Hydrierung des Ozonids 4 darstellbar. Die zu 5 strukturanalogen 2-Pyridylketone 8a-8d sowie das Tetrahydrochinolon 10 reagieren mit Phenyllithium in Äther glatt zu den erwarteten Benzylalkoholen 9a-9d bzw. 11, während die entsprechende Umsetzung von 5 zu 12 nur unter Zusatz von 1,2-Dimethoxy- äthan als Lösungsmittel durchführbar ist.
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jlac.197619760723
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Intramolekulare Aromatenalkylierungen, I Über die Synthese des 3-Hydroxy-N-methyl-8-aza-des-N-morphinans (1975)
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 1975 (1975), S. 1065-1069 
    Details
    ISSN: 0075-4617
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Intramolecular Alkylations of Aromatic Compounds. I. - On the Synthesis of 3-Hydroxy-N-methyl-8-aza-de-N-morphinanReduction of teh 5,6,7,8-tetrahydroquinolinium iodides 7a-7c with sodium borhydride gives the corresponding octahydroquinolines 5a-5c. Treatment of 5c with hydrobromic or polyphosphoric acid leads to a cyclic compound, whose structure is not identical with that of the expected compound 6.
    Notes: Die reduktion der 5,6,7,8-Tetrahydrochinoliniumjodide 7a-7c mit Natriumborhydrid fuhrt zu den korrespondierenden Octahydrochinolinen 5a-5c. Bei Behandlung von 5c mit Bromwasserstoff- oder Polyphosphorsäure läβt sich zwar ein Cyclisierungsprodukt isolieren, dessen Struktur jedoch nicht mit der erwarteten Verbindung 6 übereinstimmt.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jlac.197519750604
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Intramolekulare Aromatenalkylierungen, II1) Synthese von 1,2,3,4,4a,5,6,10b-Octahydrobenzo[f]chinolinen (1975)
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 1975 (1975), S. 1070-1080 
    Details
    ISSN: 0075-4617
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Intramolecular Alkylations of Aromatic Compounds, II1). - Synthesis of 1,2,3,4,4a,5,6,10b-Octahydrobenzo[f]quinloinesSubstituted 2-phenylethyl)pyridinium salts 8 are reduced by sodium borhydride to the corresponding tetrahydropyridine derivatives 9, which can be cyclized to the 1,2,3,4,4a,5,6,10b-Octahydrobenzo[f]quinloines 10.
    Notes: Substituierte 2-(2-Phenyläthyl)pyridiniumsalze 8 lassen sich mit Natriumborhydrid in die korrespondierenden Tetrahydropyridinderivate 9 umwandeln, die zu den 1,2,3,4,4a,5,6,10b-Octahydrobenzo[f]chinoline 10 cyclisiert werden.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jlac.197519750605
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    Intramolekulare Aromatenalkylierungen, III1) Synthese von N-Methyl-8-phenyl-1,2,3,5,6,7,8,8a-octahydrochinolin (1975)
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 1975 (1975), S. 1081-1091 
    Details
    ISSN: 0075-4617
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Intramolecular Alkylations of Aromatic Compounds, III1).  -  Synthesis of N-Methyl-8-phenyl-1,2,3,5,6,7,8,8a-octahydroquinolineThis contribution reports the synthesis of N-methyl-8-phenyl-1,2,3,5,6,7,8,8a-octahydroquinoline (3) from 8-phenyl-5,6,7,8-tetrahydroquinoline (7), which in turn has been obtained for the first time from a mixture of the isomeric enamines 8a and 8b. Surprisingly, attempts to prepare 7 from 8-aza-1-tetralone (13) and organometallic reagents failed.
    Notes: Es wird die Synthese von N-Methyl-8-phenyl-1,2,3,5,6,7,8,8a-octahydrochinolin (3) aus 8-Phenyl-5,6,7,8-tetrahydrochinolin (7), das seinerseits aus dem Isomerengemisch der Enamine 8a und 8b erstmals erhalten wird, beschrieben. Der Aufbau von 7 aus 8-Aza-1-tetralon (13) 8a und 8b erstmals erhalten wird, beschrieben. Der Aufbau von 7 uas 8-Aza- 1-tetralon (13) mit geeigneten metallorganischen Reagenzine gelingt dagegen unerwarteterweise nicht.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jlac.197519750606
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...