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  • 1975-1979  (2)
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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Inflammation research 7 (1977), S. 347-351 
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Following pupillary dilatation and immobilization of the dog with a cataleptic drug (I-Polamivet, Hoechst) the electroretinogram (ERG) was performed with the technique of Ganzfeld stimulation. The head of the dog was kept within a sphere of 60 cm diameter, the white inner surface of which could be indirectly illuminated with a stroboscope producing light flashes of 10 μsec duration. The ERG was recorded oscillographically by means of modified contact lenses. Dogs were tested for rod and cone function with luminance curves including white, blue and red stimuli and with trains of repetitive photic stimuli. Tests were performed under dark and light adaptation. The ERG of the dark-adapted dog, an indicator for the electrical activity of the rod system, was similar with that of man with respect to configuration and other characteristics. The electrical activity of the cone system was different from that of man by having a 10-fold lower sensitivity and a reduced capability for discrimination of red versus blue or white stimuli.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Inflammation research 9 (1979), S. 294-300 
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In the dog ERG flash-induced activation of the rod receptors can be selectively investigated due to relatively poor photic excitability of the cone component. The ERG was produced in immobilized dogs using the method of Ganzfeld stimulation with white light flashes of 10 μsec duration. Relatively dim flashes ranging to about 100-fold above ERG threshold lead in the dark-adapted dog to selective activation of the rod receptors. This scotopic rod ERG consists of ERG positivity including ab wave with superimposed oscillations followed by a protracted potential, presumably thec wave. Light flashes exceeding 100-fold threshold luminance cause simultaneous activation of rod and cone receptors. ERG characteristics include appearance of an early negativity, thea wave, followed byb andc waves of reduced amplitudes. In the presence of a bright background luminance of 33 ftL bright light flashes cause an ERG resulting from selective cone activation. This photopic cone ERG consists of a smalla wave followed by a smallb wave with oscillatory potentials and by marked subsequent late negativity. With increase in background luminance the late negativity increases in amplitude and occurs progressively earlier. The characteristics of the dog ERG allow selective assessment of functional changes in rod and cone receptors.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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