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  • 1970-1974  (1)
  • 1925-1929
  • 6-amino-nicotinic acid amide  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 51 (1973), S. 1074-1074 
    ISSN: 1432-1440
    Keywords: Mini-pig ; malformation ; 6-amino-nicotinic acid amide ; critical phase of embryogenesis ; Miniaturschwein ; 6-Amino-nicotinsäureamid ; Mißbildungen ; sensible embryonale Entwicklungsphase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Zur Erfassung sensibler embryonaler Entwicklungsphasen wurde graviden „Göttinger Miniaturschweinen“ 6-Amino-nicotinsäureamid intraperitoneal gespritzt. Am 10. und 16. Tag der Gestation führte die Behandlung mit 5 und 10 mg/kg Körpergewicht zu multiplen Fehlbildungen. Am 23. Tag der Gestation verursachte die Behandlung keine Fehlentwicklungen.
    Notes: Summary For the comprehension of sensible embryonal phases of development pregnant “Göttinger Miniaturschweine” were treated with intraperitoneal injection of 6-aminonicotinic acid amide with doses of 1, 5, 10 mg/kg body weight respectively. The sows were killed 1 week before the calculated birthtermin, the uteri were examined for resorption-marks and the fetuses explored for malformations. The treatment in the 10th day and 16th day of gestation with 5 and 10 mg/kg body weight caused multiple malformations. The malformation spectrum depended on the date of application. The treatment on the 23rd day of gestation caused no malformations.
    Type of Medium: Electronic Resource
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