ISSN:
1432-1912
Keywords:
Urinary Excretion
;
Methyldigoxin
;
Digoxin
;
Metabolites
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary In man the oral or intravenous administration of 4‴-methyldigoxin yields metabolites in urine which are soluble either in chloroform or in water. The chromatographic analysis reveals demethylation as the main metabolic reaction in man. In addition to methyldigoxin and digoxin small amounts of digoxigenin-bisdigitoxoside and digoxigenin-mono-digitoxoside can be detected. The water soluble metabolites represent 7% of the radioactivity excreted in 7 days reaching a maximum within the first 8 h.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00501252
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