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  • 1970-1974  (2)
  • Hypocalciämie  (1)
  • Pancreatic secretion in man  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Research in experimental medicine 160 (1973), S. 152-165 
    ISSN: 1433-8580
    Keywords: Pancreatic secretion in man ; Secretin ; Cholecystokininpancreozymin ; Hypercalcemia ; Hypocalcemia ; Calcitonin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The influences of acute changes of the serum calcium and of calcitonin (CT) on the exocrine pancreatic function have been studied in man. During stimulation with secretin and cholecystokinin-pancreozymin (CCK-PZ) Ca++-glucolactobionate, Na2-EDTA, porcine and human synthetic CT were infused i.v. Hypercalcemia provoked an increase of enzyme secretion under unstimulated and secretin stimulated conditions; however, in the case of CCK-PZ administration enzyme output was not altered. EDTA-hypocalcemia inhibited pancreatic secretion during secretin as well as during CCK-PZ infusions. CT doses above 2 MRCU caused a decrease of enzyme secretion during simultanous secretin/CCK-PZ administration by about 70–80% of the initial value without decreasing serum Ca++; doses of 0.5 MRCU and less were without effect. In none of the experiments bicarbonate secretion was affected. The results show important changes of the pancreatic enzyme secretion during acute hyper- and hypocalcemia, while calcitonin exerts an inhibitory effect during normocalcemia.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1433-8580
    Keywords: Rat pancreas ; Hypercalcemia ; Hypocalcemia ; Calcitonin ; Rattenpankreas ; Hypercalciämie ; Hypocalciämie ; Calcitonin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die stimulierte exokrine Pankreasfunktion der Ratte läßt sich durch akute Hypercalciämie, ÄDTA-Hypocalciämie oder Calcitoningabe nicht beeinflussen. Dieses Verhalten steht im Gegensatz zur Reaktion des Magens der Ratte auf Calciumreize.
    Notes: Summary In the rat, stimulated exocrine pancreatic secretion is not influenced by acute hypercalcemia, EDTA hypocalcemia or calcitonin administration. This unresponsiveness is in contrast to the reaction of the rat stomach to calcemic challenges.
    Type of Medium: Electronic Resource
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