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  • 1970-1974  (2)
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  • 1
    Electronic Resource
    Electronic Resource
    The scatter of intracellular ionic concentration in the lobster circumesophageal axon (1972)
    Springer
    Journal of comparative physiology 81 (1972), S. 89-98 
    Details
    ISSN: 1432-1351
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The intracellular potassium and sodium concentrations of the lobster circumesophageal axon was measured with an ultramicro integrative flame photometer. The average concentration of 376.1 mM/l vol for potassium and 63.8 mM/l vol for sodium that was determined was correlated with electrophysiological data. The large scatter of the concentration in individual axons is compared with measurements by other investigators and is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00693552
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Spontaneous conductance changes, multilevel conductance states and negative differential resistance in oxidized cholesterol black lipid membranes (1974)
    Springer
    The journal of membrane biology 17 (1974), S. 201-212 
    Details
    ISSN: 1432-1424
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Summary Oxidized cholesterol lipid films were studied under voltage clamp conditions. Certain kinds of conductance phenomena closely resembling effects described in the literature and atributed to various additives were observed with unmodified lipid films. These include spontaneous conductance changes, multilevel conductance states and negative resistance phenomena in films formed from aged oxidized cholesterol-inhydrocarbon solutions. The multilevel conductance state manifests itself in the form of step changes in current under voltage clamp, the magnitudes of which correspond to conductance intervals of 5±2×10−10 mho and its multiples in 0.1n sodium chloride. These steps are attributed to channels that form in the film. Under certain conditions it has been observed that the action of the electric field was to close channels that were open at lower voltages. Under these conditions the current-voltage plot shows a distinct region of “negative differential” resistance. Films generated from freshly prepared oxidized cholesterol solutions did not exhibit multistable phenomena but under a prolonged voltage clamp the membrane conductance went into a transition from a stable, relatively noise-free-current state to a gradually increasing current with a large noise component. This sequence generally signalled imminent breakdown but the membrane could spontaneously revert to the original high-resistance, low-noise state. These kinds of intrinsic behavior sufficiently resemble certain effects produced by additives to merit special consideration during membrane reconstitution experiments.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01870182
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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