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  • 1970-1974  (2)
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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Virchows Archiv 362 (1974), S. 207-221 
    ISSN: 1432-2307
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Ultrastructural changes observed in a muscle biopsy from a patient suffering with “Stiff-man” syndrome are described. In addition to nonspecific degenerative and regenerative changes in the myofibers, the site of maximal pathology seems to be the myoneural junction, with mainly hypertrophic and hyperplastic changes of the motor end plates. The possible pathophysiological factors causing these inductive changes are discussed.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Histochemistry and cell biology 38 (1974), S. 143-153 
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Calcium concentration and intracellular localization were investigated using the electron microscopic X-ray analyser (EMMA-4) in preparations of dog myocardial tissues fixed either in glutaraldehyde, osmium tetroxide or potassium pyroantimonate plus osmium tetroxide. Calcium could be detected with all the fixatives, but at varying efficiency. Glutaraldehyde fixation showed small detectable amounts of calcium and without special localization except in the nucleus. Osmium fixation showed much higher, but still poorly localized concentrations. The pyroantimonate technique produced the highest calcium concentrations and loci of statistically significant concentrations. Preparations stained with uranyl acetate or lead citrate showed well-visualized precipitates but no detectable calcium concentrations.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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